Evidence map›Paper›PMID 40386097›Full record

ArticleIranian journal of veterinary research2025

Immune efficacy of

G Qiang, L Yajing, Z Shiji, T Jiayu, L Jingwen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

G QiangDepartment of Bioengineering, Faculty of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
L YajingMSc Student in Microbiology, Department of Bioengineering, Faculty of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
Z ShijiMSc Student in Microbiology, Department of Bioengineering, Faculty of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
T JiayuMSc Student in Microbiology, Department of Bioengineering, Faculty of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
L JingwenMSc Student in Food Microbiology, Henan Engineering Research Center of Food Microbiology, Faculty of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aims: This study aimed to evaluate the immune efficacy of a chitosan nanoparticle DNA vaccine of the Methods: The naked DNA vaccine based on the Results: The particle size of the chitosan nanoparticle DNA vaccine was approximately 200 nm and close to spherical; the encapsulation efficiency was 95.88%, and it could effectively resist degradation by DNase. Following vaccination, serum antibodies, stimulation index (SI) value, and concentrations of IFN-γ, IL-2, and IL-4 in chickens immunized with the chitosan nanoparticle DNA vaccine were significantly higher than those that were vaccinated with the naked DNA vaccine (P<0.05). The protective rates of poprH, CoprH, OMP vaccine, and inactive vaccine groups were 55%, 75%, 75%, and 90%, respectively. Conclusion: Chitosan could significantly enhance the immune response and protection provided by the naked DNA vaccine of the

Indexed as

Chitosan nanoparticle DNA vaccineImmune efficacyNaked DNA vaccineoprH genePseudomonas aeruginosa

Identifiers

PMID40386097
PMCPMC12085210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.