ArticleInternational journal of cardiology. Heart & vasculature2025
The role of impaired iron transport on exercise performance and prognosis in patients with chronic heart failure.
Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Recent highlights from the International Journal of Cardiology Heart & Vasculature: cardiometabolic disease.International journal of cardiology. Heart & vasculature · 2025Article
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15 authors.
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Abstract
Background: Iron deficiency (ID) is frequent in chronic heart failure (HF). Among HF-ID patients those with impaired iron transport (IIT) (Transferrin saturation (TSAT) < 20 %) have the worst prognosis. In HF survival is strictly related to exercise limitation but the link between IIT, exercise limitation and survival is at present undefined. Methods: We evaluated in 999 consecutive patients hospitalized for worsening HF whether IIT affects prognosis through cardiopulmonary exercise test (CPET), i.e. peak oxygen uptake (VO Results: PeakVO Conclusions: The adverse impacts of low TSAT on prognosis are in part direct and in part mediated by mechanisms related to reduced peakVO
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