Evidence map›Paper›PMID 40385975›Full record

ArticleTherapeutic advances in infectious disease

Antibiotic resistance patterns in uropathogens: insights from a Nepalese tertiary care setting.

Rahi Bikram Thapa, Sabin Shrestha, Pharsuram Adhikari, Rajeev Shrestha

Abstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Antibiogram and Detection of Resistant Genes inInternational journal of microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rahi Bikram ThapaHospital Development and Medical Services Division, Ministry of Health, Koshi Province, Biratnagar 9, Devkota Chowk, Morang 56613, Nepal.ORCID https://orcid.org/0009-0002-2675-7856
Sabin ShresthaDepartment of Pharmacy, Manmohan Memorial Institute of Health Science, Kathmandu, Nepal.ORCID https://orcid.org/0009-0005-2491-934X
Pharsuram AdhikariDepartment of Pharmacy, Manmohan Memorial Institute of Health Science, Kathmandu, Nepal.ORCID https://orcid.org/0000-0001-6121-3868
Rajeev ShresthaNIHR Newcastle Patient Safety Research Collaboration, Newcastle University, Newcastle-upon-Tyne, UK.ORCID https://orcid.org/0000-0003-1822-3969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial resistance in uropathogens is increasing globally, particularly in resource-limited settings such as Nepal, limiting treatment options. Objectives: This study aimed to evaluate the antimicrobial resistance patterns of uropathogens isolated from patients with urinary tract infections (UTIs) in a tertiary care hospital in central Nepal. Design: This study utilized a retrospective study design. Methods: We retrospectively observed medical records from August 2023 to February 2024 at Manmohan Memorial Teaching Hospital in Nepal, focusing on patients with significant bacterial growth in urine samples and antibiotic sensitivity analysis for resistance trends. Results: Conclusion: Empirical therapy, including nitrofurantoin and aminoglycosides, is a viable option for combating antimicrobial resistance in Nepal, necessitating region-specific surveillance and multicentre studies.

Indexed as

antibiotic resistance patternsantimicrobial resistanceE. coliNepalurinary tract infections

Identifiers

PMID40385975
PMCPMC12084692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.