ArticleCureus2025
Management of Spontaneous Corneal Perforation in Undiagnosed Primary Sjögren's Syndrome.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spontaneous corneal perforation is a true diagnostic and therapeutic emergency that can reveal autoimmune diseases such as primary Gougerot-Sjögren syndrome (pSS). We report the case of a 59-year-old female patient with no notable medical history who presented with a painful unilateral red eye and decreased visual acuity. Examination revealed a unilateral paracentral corneal perforation, which was subsequently confirmed to be associated with pSS based on the positivity of anti-SSA/SSB antibodies and a minor salivary gland biopsy showing lymphocytic infiltration, without any signs suggestive of an associated systemic disease. The patient underwent conjunctival covering and received systemic treatment with corticosteroids and immunosuppressants, leading to a favorable clinical outcome. This case highlights the importance of early diagnosis and a multidisciplinary approach to prevent severe complications associated with pSS.
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