Evidence map›Paper›PMID 40385883›Full record

ArticleCureus2025

First-Trimester Radical Hysterectomy for Bulky Cervical Cancer: A Case Report on Oncologic and Reproductive Considerations.

Munachiso I Ndukwe, Denisa Pohankova, Petr Halada, Jan Laco, Martin Stepan, Tatana Reslova, Petra Bretova, Dominik Karasek, Domink Habes, Adam Rezac and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Munachiso I NdukweDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Denisa PohankovaDepartment of Oncology and Radiotherapy, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Petr HaladaDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Jan LacoThe Fingerland Department of Pathology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Martin StepanDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Tatana ReslovaDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Petra BretovaDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Dominik KarasekDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Domink HabesDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Adam RezacDepartment of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Igor SirakDepartment of Oncology and Radiotherapy, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of cervical cancer during the first trimester of pregnancy requires a multidisciplinary approach that considers medical, psychological, and social factors. This report details the case of a patient diagnosed preoperatively with bulky early-stage cervical cancer at nine weeks of gestation, during an evaluation initially intended for pregnancy termination. While definitive chemoradiotherapy is the standard treatment for early-stage bulky cervical tumors, the treatment strategy, in this case, was influenced by the patient's decision to terminate the pregnancy without delay. A radical hysterectomy with pelvic lymphadenectomy was successfully performed at 10 weeks of gestation. The patient experienced an uneventful postoperative recovery and was subsequently advised to undergo adjuvant chemoradiotherapy. This case underscores the importance of an individualized management plan that prioritizes maternal health while respecting reproductive rights and patient autonomy.

Indexed as

open radical hysterectomypregnancysurgical abortionuterine cervical cancerwomen's reproductive rights

Identifiers

PMID40385883
PMCPMC12085773

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.