Evidence map›Paper›PMID 40385752›Full record

ArticleCureus2025

Dengue Fever-Induced Complete Heart Block (Cardiac Dengue) Requiring Permanent Pacemaker Implantation in a 53-Year-Old Man: A Case Report.

Maitha K Alnuaimi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Maitha K AlnuaimiInternal Medicine, Tawam Hospital, Abu Dhabi, ARE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue fever is an endemic mosquito-borne viral infection in many tropical and subtropical regions. While its common manifestations include high-grade fever, rash, and myalgia, cardiac complications, particularly complete heart block, are rare but potentially life-threatening, underscoring the importance of vigilance. A 53-year-old man with type 2 diabetes mellitus and hypertension presented with dizziness, weakness, and a five-day history of high-grade fever with chills. He lived in a dengue-endemic area and denied any recent travel. Physical examination revealed bradyarrhythmia (38-49 beats per minute) and hypotension (99/72 millimeters of mercury). Laboratory tests confirmed acute dengue infection. Despite supportive care and temporary pacing, the patient's intrinsic atrioventricular conduction showed no recovery, leading to persistent pacemaker dependence. On hospital day 17, a permanent dual-chamber pacemaker was implanted. He stabilized after the procedure and was discharged with close follow-up. The diagnosis of dengue was established using standard clinical criteria, confirmed by serologies for immunoglobulin M and immunoglobulin G and reverse transcription polymerase chain reaction. Comprehensive investigations excluded other bradyarrhythmia causes, such as Lyme disease, sarcoidosis, and myocarditis, supporting dengue as the sole etiology. This case highlights the rare but significant phenomenon of dengue-induced complete heart block, emphasizing that long-term pacemaker support may be necessary if conduction fails to recover. By adding to the limited data on dengue-associated advanced conduction disturbances, this case underscores the need for early recognition and multidisciplinary management to improve outcomes.

Indexed as

bradyarrhythmiacardiac complicationscomplete heart blockdengue feverpermanent pacemaker

Identifiers

PMID40385752
PMCPMC12083512

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.