ArticleCureus2025
Unlocking the Heart: A 10-Year Experience of Interventions and Outcomes of Constrictive Pericarditis in a Northeast Indian Tertiary Care Center.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionChronic constrictive pericarditis (CCP) is a debilitating condition characterized by thickening and fibrosis of the pericardium, leading to impaired diastolic filling and reduced cardiac output. Patients typically present with symptoms of right-sided heart failure, such as peripheral edema, ascites, and dyspnea. Definitive treatment involves surgical pericardiectomy, which aims to remove the constrictive pericardium and restore normal cardiac function. This study aims to assess the operative and short-term outcome of this rare disease in the northeastern part of India.
methodsRetrospective data records of patients who underwent pericardiectomy were analyzed from 2011 to 2020.
resultsOf the patients, 20 (47.6%) were in New York Heart Association (NYHA) class III, and 12 (28.6%) were in NYHA class IV. Hyperbilirubinemia was seen in 29 (69%) patients, and hypoalbuminemia in 18 (42.9%) patients. Radical pericardiectomy was done in 36 (85.7%) cases, and the waffle operation was done in five (12%) cases. The mean ICU stay post procedure was 5.81 days (2-18 days), and the mean hospital stay was 19.6 days (2-49 days). The in-hospital mortality rate was 14.6% (six cases), and the cause of death in all cases was persistent low cardiac output.
conclusionPericardiectomy is the only definitive treatment for symptomatic CCP, and it gives a chance to the patient for a full recovery from the chronic morbidity and mortality it is associated with. The right time for surgical intervention is still not clear and needs to be individualized for each patient, but the earlier the intervention, the better the short-term survival.
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