Evidence map›Paper›PMID 40385706›Full record

ReviewAnnals of Ibadan postgraduate medicine2024

BREASTFEEDING AND ACUTE RESPIRATORY INFECTION (ARI) IN INFANTS: A SYSTEMATIC REVIEW IN NIGERIA.

A George, S Bonne, E N Ekpenyong, E N Edem, S Ajayi

Abstract readReview
In one paragraph

Review in Annals of Ibadan postgraduate medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A GeorgeThe Oxford Vaccine Group, Department of Paediatrics, University of Oxford, England.
S BonneFaculty of Medicine, McGill University, Canada.
E N EkpenyongDepartment of Haematology and Blood Bank, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria.
E N EdemDepartment of Medical Microbiology and Parasitology, Faculty of Basic Clinical Sciences, University of Uyo, Nigeria.
S AjayiThe Oxford Vaccine Group, Department of Paediatrics, University of Oxford, England.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute Respiratory Infections (ARIs) significantly contribute to infant morbidity and mortality worldwide, especially in developing countries like Nigeria, where factors such as inadequate nutrition, poor environmental conditions, and partial immunization increase their incidence, while exclusive breastfeeding (EBF) offers immune protection that can reduce their incidence and severity. Therefore this review assessed the role of breastfeeding, especially exclusive breastfeeding, in reducing the risk and severity of ARIs in Nigerian infants, while also evaluating factors influencing breastfeeding practices. Methods: A systematic review was conducted following PRISMA guidelines, involving a comprehensive search of databases such as PubMed, Scopus, ScienceDirect, Google Scholar, and African Journals Online. Twelve studies conducted between 2004 and 2024 focusing on breastfeeding practices and their impact on ARIs in Nigerian infants aged 0-6 months were selected. The review focused on primary studies with observational and cohort designs. Results: The review found that exclusive breastfeeding significantly reduces the risk of ARIs in infants, with non-exclusively breastfed infants facing a fourfold increase in ARI risk. Breast milk contains immunologically active components like secretory IgA, lactoferrin, and lysozyme, which enhance immune defenses and reduce the severity of ARIs such as pneumonia. However, only 25-40% of infants in Nigeria are exclusively breastfed for six months due to cultural beliefs, maternal employment, lack of education etc. Conclusion: Exclusive breastfeeding significantly protects Nigerian infants against ARIs, but cultural misconceptions, socioeconomic barriers, insufficient maternal education etc hinder optimal practices, necessitating targeted public health initiatives and policy interventions to improve infant health outcomes.

Indexed as

Acute respiratory infectionsBreastfeeding practicesExclusive breastfeedingInfant healthPublic health strategies

Identifiers

PMID40385706
PMCPMC12082678

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.