Evidence map›Paper›PMID 40385693›Full record

ReviewOncology letters2025

Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review).

Xing Xu, Xue Zhang, Yang Zhao, Xiaoyang Zhang, Hongfang Tuo

Abstract readReview
In one paragraph

Review in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xing XuDepartment of Hepatobiliary Surgery, Hebei General Hospital, Shijiazhuang, Hebei 050057, P.R. China.
Xue ZhangDepartment of Pathology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Yang ZhaoDepartment of Hepatobiliary Surgery, Hebei General Hospital, Shijiazhuang, Hebei 050057, P.R. China.
Xiaoyang ZhangDepartment of Hepatobiliary Surgery, Hebei General Hospital, Shijiazhuang, Hebei 050057, P.R. China.
Hongfang TuoDepartment of Hepatobiliary Surgery, Hebei General Hospital, Shijiazhuang, Hebei 050057, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hepatocellular carcinoma (HCC) represents a malignancy of notable clinical concern, marked by elevated global incidence and mortality rates. Despite advancements in therapeutic modalities, HCC management remains challenged by the insidious onset of early-stage disease and the limited efficacy of late-stage surgical interventions. Transcatheter arterial chemoembolization (TACE) has evolved as a pivotal intervention for HCC, with recent innovations fostering synergistic combination strategies to augment therapeutic outcomes. Synthesizing contemporary clinical evidence and anticipating future advancements in TACE-based multimodal approaches is imperative to refine therapeutic paradigms and optimize patient prognoses. The present review critically evaluates the current landscape of TACE-centered multimodal therapies and explores emerging innovations poised to redefine therapeutic frontiers in HCC management.

Indexed as

hepatocellular carcinomaimmunotherapymolecular targeted therapytherapeutic chemoembolizationtherapy

Identifiers

PMID40385693
PMCPMC12082388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.