Evidence map›Paper›PMID 40385593›Full record

ArticleBioinformatics advances2025

cOmicsArt-a customizable Omics Analysis and reporting tool.

Lea Seep, Paul Jonas Jost, Clivia Lisowski, Hao Huang, Stephan Grein, Hildigunnur Hermannsdottir, Katharina Kuellmer, Tobias Fromme, Martin Klingenspor, Elvira Mass and 2 more

Abstract read
In one paragraph

Article in Bioinformatics advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lea SeepComputational Biology, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn 53115, Germany.ORCID https://orcid.org/0000-0002-0399-1896
Paul Jonas JostComputational Biology, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn 53115, Germany.ORCID https://orcid.org/0000-0001-7613-6244
Clivia LisowskiInstitute of Molecular Medicine and Experimental Immunology (IMMEI), University Hospital of Bonn, University of Bonn, Bonn 53127, Germany.ORCID https://orcid.org/0000-0003-1659-6315
Hao HuangDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn 53115, Germany.ORCID https://orcid.org/0000-0003-3878-3947
Stephan GreinComputational Biology, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn 53115, Germany.ORCID https://orcid.org/0000-0001-9524-6633
Hildigunnur HermannsdottirChair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising 85354, Germany.ORCID https://orcid.org/0009-0001-1548-9828
Katharina KuellmerChair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising 85354, Germany.ORCID https://orcid.org/0009-0001-1753-0978
Tobias FrommeChair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising 85354, Germany.ORCID https://orcid.org/0000-0001-9150-2513
Martin KlingensporChair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising 85354, Germany.ORCID https://orcid.org/0000-0002-4502-6664
Elvira MassDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn 53115, Germany.ORCID https://orcid.org/0000-0003-2318-2356
Christian KurtsInstitute of Molecular Medicine and Experimental Immunology (IMMEI), University Hospital of Bonn, University of Bonn, Bonn 53127, Germany.ORCID https://orcid.org/0000-0002-6620-2401
Jan HasenauerComputational Biology, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn 53115, Germany.ORCID https://orcid.org/0000-0002-4935-3312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: The availability of bulk-omic data is steadily increasing, necessitating collaborative efforts between experimental and computational researchers. While software tools with graphical user interfaces (GUIs) enable rapid and interactive data assessment, they are limited to pre-implemented methods, often requiring transitions to custom code for further adjustments. However, the most available tools lack GUI-independent reproducibility such as direct integration with R, resulting in very limited support for transition. Results: We introduce the customizable Omics Analysis and reporting tool-cOmicsArt. cOmicsArt aims to enhance collaboration through integration of GUI-based analysis with R. The GUI allows researchers to perform user-friendly exploratory and statistical analyses with interactive visualizations and automatic documentation. Downloadable R scripts and results ensure reproducibility and seamless integration with R, supporting both novice and experienced programmers by enabling easy customizations and serving as a foundation for more advanced analyses. This versatility also allows for usage in educational settings guiding students from GUI-based analysis to R Code. Availability and implementation: cOmicsArt is freely available at https://shiny.iaas.uni-bonn.de/cOmicsArt/. User documentation is available at https://icb-dcm.github.io/cOmicsArt/. Source code is available at https://github.com/ICB-DCM/cOmicsArt. A docker available from https://hub.docker.com/r/pauljonasjost/comicsart/tags. A snapshot upon publication available from https://zenodo.org/records/14907620. A screen recording of cOmicsArt is available at: https://www.youtube.com/watch?v=pTGjtIYQOakp.

Identifiers

PMID40385593
PMCPMC12085238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.