Evidence map›Paper›PMID 40385577›Full record

SynthesisFrontiers in medicine2025

The incidence of metabolic syndrome in psoriasis patients and its correlation with disease activity: a systematic review and meta-analysis.

Zongyang Li, Zheng Gu, Jingyu Xiang, Xiaoyan Zhang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. TopicalPharmaceutics · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zongyang LiGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Zheng GuGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Jingyu XiangGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Xiaoyan ZhangDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the association between psoriasis and metabolic syndrome (MetS) and analyze the impact of disease activity on the risk of MetS occurrence. Method: This systematic review and meta-analysis used computer searches to search for relevant literature on psoriasis and MetS in databases including China National Knowledge Infrastructure (CNKI), PubMed, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL) and Embase. The search period was from the establishment of the database to February 8, 2025. Inclusion in case-control, cohort studies and cross-sectional, with language restrictions in Chinese and English during retrieval. After independent screening of literature, extraction of data, and evaluation of risk bias for inclusion in the study by two evaluators, meta-analysis and subgroup analysis were conducted using Stata17.0 software. Result: A total of 12 studies were analyzed, encompassing 9,641 patients with psoriasis and 2,554 patients suffering from MetS alongside psoriasis. The incidence of metabolic syndrome in psoriasis patients was analyzed and the combined effect size was 26.49% [95% CI (25.61, 27.39%)]. Results from the meta-analysis indicated that, in comparison to the control group, psoriasis patients demonstrated a heightened risk of developing MetS [OR = 1.27, 95% CI (1.21-1.33), Conclusion: Psoriasis is positively correlated with MetS risk, and increased disease activity further increases the risk. It is necessary to strengthen screening for metabolic abnormalities and multidisciplinary management.

Indexed as

disease activityincidencemetametabolic syndromepsoriasis

Identifiers

PMID40385577
PMCPMC12081259

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.