Evidence map›Paper›PMID 40385539›Full record

ReviewBioengineering & translational medicine2025

Mpox disease, diagnosis, and point of care platforms.

Nazente Atceken, Ikra Bayaki, Berk Can, Defne Yigci, Savas Tasoglu

Abstract readReview
In one paragraph

Review in Bioengineering & translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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  7. Mpox disease, diagnosis, and point of care platforms.Bioengineering & translational medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nazente AtcekenSchool of Biomedical Sciences and Engineering Koç University Istanbul Turkey.
Ikra BayakiDepartment of Molecular Biology and Genetics, Faculty of Science and Letters Yıldız Technical University Istanbul Turkey.
Berk CanInstitute for Cell Biology University of Bonn Bonn Germany.
Defne YigciSchool of Medicine Koç University Istanbul Turkey.
Savas TasogluSchool of Biomedical Sciences and Engineering Koç University Istanbul Turkey.ORCID https://orcid.org/0000-0003-4604-217X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Mpox disease (MPX) is an endemic zoonotic disease that develops when patients are infected with the Mpox virus (MPXV). MPXV shares a high level of genetic similarity to other poxviruses and the clinical presentation of MPX is similar to other poxvirus infections which can result in a delay in diagnosis. In addition, the MPXV virus is phylogenetically divided into two different clades which affects the severity of disease. In recent years, there has been an unusual worldwide spread of MPXV, leading to a global public health problem. The most important step in the fight against MPX is rapid, highly specific, and accurate diagnosis. Following the rapid spread of disease in recent years, efforts to develop diagnostic tests have gained momentum. Here, MPX, MPX epidemiology, and MPX diagnostic tests are discussed. Furthermore, biochemical diagnostic tests, molecular diagnostic tests and their development, and point-of-care (PoC) diagnostic applications are reviewed. Molecular diagnostic technologies such as polymerase chain reaction, recombinase polymerase amplification, and loop-mediated isothermal amplification methods that detect MPX are evaluated. Additionally, next-generation combined molecular techniques and their importance in PoC transition are explored.

Indexed as

loop‐mediated isothermal amplification (LAMP)Mpox (MPX)point‐of‐care (PoC) applicationspolymerase chain reaction (PCR)recombinase polymerase amplification (RPA)

Identifiers

PMID40385539
PMCPMC12079464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.