Evidence map›Paper›PMID 40385496›Full record

ArticleInternational journal of nanomedicine2025

Dopamine and Mn(II) Chelate Covalent-Doping Coated Ti(IV)-Nanotheranostics for Magnetic Resonance Imaging Guided Phototherapy in Oral Cancer.

Zhenghui Li, Xufei Bian, Huiyu Wu, Ling He, Zuhua Zeng, Lei Zhong, Yao Liu, Yu Li, Guihao Hu, Fanglin Mi and 2 more

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhenghui Li *Medical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Xufei Bian *Medical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Huiyu WuMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Ling HeMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Zuhua ZengMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Lei ZhongMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Yao LiuMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Yu LiMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Guihao HuMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Fanglin MiDepartment of Stomatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Zhen LiuDepartment of Stomatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.
Jiang ZhuMedical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Phototherapy have gained significant traction in the treatment of tumors. However, the successful implementation of these therapies relies on photosensitizers with superior properties and precise guidance mechanisms. Methods: In this study, we introduce an innovative method for the surface modification of titanium dioxide (TiO Results: This modification extends TiO Conclusion: This multifunctional nanotheranostic, integrating high relaxivity with synergistic PTT/PDT for MR imaging-guided phototherapy, holds great potential for applications in the early diagnosis, noninvasive treatment, and prognostic evaluation of oral squamous cell carcinoma.

Indexed as

DopamineManganeseMouth NeoplasmsPhototherapyTitaniumAnimalsCell Line, TumorHumansMagnetic Resonance ImagingMiceMice, Inbred BALB CMice, NudeNanoparticlesPhotochemotherapyPhotosensitizing AgentsTheranostic NanomedicineDopamineManganesePhotosensitizing AgentsTitaniumtitanium dioxidehorseradish peroxidase catalysisoral squamous cell carcinomaphotodynamic therapyphotothermal therapytitanium dioxide

Identifiers

PMID40385496
PMCPMC12083491

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.