ArticleAnnals of gastroenterological surgery2025
Combined effect of frailty and sarcopenia on postoperative complications in older adults undergoing curative surgery for hepato-biliary-pancreatic cancer.
Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Frailty and sarcopenia proxies are associated with postoperative outcomes after abdominal wall reconstruction: a national database analysis.Surgical endoscopy · 2026Article
- Article
- Clinical significance of preoperative oral frailty and malnutrition in predicting the surgical outcomes of Gastrointestinal cancers.Surgery today · 2026Article
- Evaluation of the Japanese National clinical database risk calculator as a surrogate frailty assessment tool for older adults with colorectal cancer.Surgery today · 2026Article
- Frailty in hepatobiliary and pancreatic (HBP) surgery: a narrative review toward an HBP-specific, implementation-oriented framework.Gland surgery · 2026Review
- Psoas Muscle Volume as a Predictor of Postoperative Complications in Patients Undergoing Emergency Surgery for Strangulated Small Bowel Obstruction: A Retrospective Single-Center Study.Annals of gastroenterological surgery · 2026Article
- Nutritional Status and Chemotherapy Completion in Resectable Pancreatic Cancer: A Narrative Review.Current oncology (Toronto, Ont.) · 2025Review
- Combined effect of frailty and sarcopenia on postoperative complications in older adults undergoing curative surgery for hepato-biliary-pancreatic cancer.Annals of gastroenterological surgery · 2025Article
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10 authors.
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Abstract
Aim: Older adults with cancer are often at increased risk for postoperative complications following major surgeries. This study aimed to evaluate the combined role of frailty and sarcopenia in predicting postoperative complications in older adults with hepatobiliary and pancreatic cancer undergoing surgery. Methods: This retrospective study included 107 Japanese patients who underwent comprehensive geriatric assessment (CGA) at the geriatric oncology service before cancer treatment decisions and subsequent curative surgery for hepatobiliary and pancreatic cancer. Frailty status was measured using the validated 10-item frailty index based on a CGA (FI-CGA-10) and categorized as fit, prefrail, or frail. Sarcopenia was assessed using bioelectrical impedance analysis and grip strength. The primary outcome was postoperative complications, defined as Clavien-Dindo grade ≥ III, within 1 month of surgery. Results: The median age of the 107 patients was 79 (range, 75-89) years. Patients were categorized as fit ( Conclusion: In this study, patients classified as prefrail/frail and sarcopenic were at significantly higher risk for postoperative complications.
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