Evidence map›Paper›PMID 40385312›Full record

ArticleFrontiers in digital health2025

Vocal biomarkers in heart failure-design, rationale and baseline characteristics of the AHF-Voice study.

Fabian Kerwagen, Maximilian Bauser, Magdalena Baur, Fabian Kraus, Caroline Morbach, Rüdiger Pryss, Kristen Rak, Stefan Frantz, Michael Weber, Julia Hoxha and 1 more

Abstract read
In one paragraph

Article in Frontiers in digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Editorial: listening for congestion in heart failure.European heart journal. Digital health · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fabian Kerwagen *Department of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Maximilian Bauser *Department of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Magdalena BaurDepartment of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Fabian KrausDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, University of Würzburg, Würzburg, Germany.
Caroline MorbachDepartment of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Rüdiger PryssInstitute of Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.
Kristen RakDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, University of Würzburg, Würzburg, Germany.
Stefan FrantzDepartment of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Michael WeberCosinuss GmBH, München, Germany.
Julia HoxhaZANA Technologies GmbH, Karlsruhe, Germany.
Stefan StörkDepartment of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute heart failure (AHF) is a life-threatening condition and a common cause of hospitalization. The defining clinical feature of AHF is volume overload, leading to pulmonary and peripheral edema and consequently to weight gain. Vocal biomarkers have the potential to facilitate the early detection of worsening HF and the prevention of AHF episodes by offering a non-invasive, low-barrier monitoring tool. The AHF-Voice study is a prospective monocentric cohort study designed to investigate the trajectories of voice alterations during and after episodes of AHF, identify potential vocal biomarkers, and enhance the understanding of the pathophysiological mechanisms underlying these voice changes. It will examine the characteristics and determinants of vocal biomarkers, analyzing their correlations with patients' clinical status and comparing them to alternative clinical parameters in HF. Further, it aims to determine whether specific vocal biomarkers can accurately map different HF phenotypes and assess their association with patient trajectories

Indexed as

decompensationdigital healthheart failureremote patient managementstudy designtelemonitoringvocal biomarkervoice

Identifiers

PMID40385312
PMCPMC12082658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.