Evidence map›Paper›PMID 40385255›Full record

ArticleCureus2025

Successful Treatment of a Nonunion Fracture of the Femur With Extracorporeal Shockwave Therapy: An Evidence-Based Case Report.

Theodore Tandiono, Jessica Amelinda Mintarjo, Nunung Nugroho

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Theodore TandionoDepartment of Physical Medicine and Rehabilitation, Primasatya Husada Citra Hospital, Surabaya, IDN.
Jessica Amelinda MintarjoDepartment of Physical Medicine and Rehabilitation, Primasatya Husada Citra Hospital, Surabaya, IDN.
Nunung NugrohoDepartment of Physical Medicine and Rehabilitation, Primasatya Husada Citra Hospital, Surabaya, IDN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonunion fractures, especially of the femur, pose a considerable difficulty in orthopedic management due to their propensity to result in enduring physical disability and psychological complications. Conventional surgical procedures, although efficacious, may entail difficulties and have a reduced success rate for atrophic nonunions. Extracorporeal shockwave therapy (ESWT) has arisen as a viable non-invasive option, facilitating bone regeneration via many biological mechanisms. This case report describes the management of a 40-year-old male patient with a distal-third open femoral fracture resulting from a motor vehicle accident. Despite receiving open reduction internal fixation and an extensive rehabilitation regimen, the patient had little callus development after six months. ESWT was commenced once weekly for 23 weeks, combined with ultrasonic low-intensity pulsed ultrasound (LIPUS) therapy and leg extension exercises. The patient had full callus formation on the femur and made a full recovery. The comprehensive literature evaluation demonstrates that ESWT can achieve a healing rate of around 73% for nonunion femoral fractures. The therapy's effectiveness is due to its capacity to induce osteogenic responses, promote osteoblast development, and suppress osteoclast production. This non-invasive method diminishes the necessity for supplementary surgical interventions and related complications. Additional research is required to develop standardized methods and refine therapy parameters, guaranteeing consistent and dependable results across various patient groups.

Indexed as

eswtevidence-based case reportnon-invasive treatmentnonunion femur fracturenonunion fracture

Identifiers

PMID40385255
PMCPMC12083416

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.