ArticleInternational journal of ophthalmology2025
Corneal light scattering and anterior segment findings in rheumatoid arthritis patients: a prospective study on disease monitoring.
Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimTo evaluate changes in corneal light scattering and anterior segment parameters in newly diagnosed rheumatoid arthritis (RA) patients who achieved remission with systemic treatment, compared to healthy controls.
methodsA cross-sectional study was conducted at a tertiary care hospital, in ophthalmology, and rheumatology departments. A total of 42 RA patients (13 men and 29 women) and 56 healthy individuals (23 men 33 women) underwent comprehensive ophthalmologic evaluations, including Scheimpflug corneal densitometry and Pentacam HR measurements. Those who initiated systemic treatment for RA were monitored at first, third, and sixth-month follow-ups. Participants who achieved remission at each follow-up assessment were included.
resultsSignificant differences in corneal densitometry were observed, with higher values in RA patients, particularly in the middle and posterior layers. Anterior segment parameters such as anterior chamber volume and angle were significantly reduced in RA patients compared to other groups (
conclusionThe study underscores the potential utility of corneal densitometry and anterior segment analysis as sensitive indicators of subclinical ocular involvement in RA, offering insights into disease progression and treatment efficacy. These findings highlight the importance of early detection and regular monitoring in preventing vision-threatening complications in RA patients.
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