Evidence map›Paper›PMID 40385113›Full record

ArticleInternational journal of ophthalmology2025

Safety evaluation after LASIK surgery based on the linear creep property: a finite element analysis.

Ji-Xi Guo, Xue-Feng Li, Xin-Chao Wang, Xin-Heng Zhao, Yan Wang, Li-Hua Fang

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Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ji-Xi GuoKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang 330063, Jiangxi Province, China.
Xue-Feng LiKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang 330063, Jiangxi Province, China.
Xin-Chao WangKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang 330063, Jiangxi Province, China.
Xin-Heng ZhaoTianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital; Nankai University Eye Institute, Nankai University; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300000, China.
Yan WangTianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital; Nankai University Eye Institute, Nankai University; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300000, China.
Li-Hua FangKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang 330063, Jiangxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effect of the percent tissue altered (PTA) on the safety after laser-assisted

methodsThe linear creep characteristics of the cornea were characterized by the generalized Kelvin-Voigt constitutive relationship with five parameters. Then, the displacement and stress distribution on the anterior and posterior surfaces of the cornea were analyzed by constructing the eye model with different PTA.

resultsWhen PTA was above 39%, the vertex displacements under physiological intraocular pressure (IOP, 15 mm Hg) exceeded that of the preoperative glaucoma under average IOP. That is, an excessively high displacement value was found. In addition, with the increase of PTA, the central cornea was stretched thinner and more obviously due to IOP. When PTA was above 39%, the stress at the center of the anterior surface of the residual stroma was more than 20% larger than that of the normal human eye. The residual stroma was forced to stretch more severely due to excessive stress on the anterior surface. This resulted in deformation of the stroma and induced corneal ectasia. Meanwhile, the postoperative vertex displacement increased with the decrease in viscosity ratio.

conclusionPTA less than 39% is the safe range for LASIK surgery. This study may provide a reliable numerical basis for postoperative corneal dilatation and the outcomes after refractive surgery.

Indexed as

finite elementlaser-assisted in situ keratomileusispercent tissue alteredvertex displacement

Identifiers

PMID40385113
PMCPMC12043300

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