ArticleInternational journal of ophthalmology2025
Reduced choroidal vascular index and choroid structural changes extended beyond subfoveal area in chronic central serous chorioretinopathy eyes with macular neovascularization.
Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimTo investigate the choroidal vascular index (CVI) and the choroidal structural changes beyond the subfoveal area (analyzed across a 20 mm×24 mm scanning area) in eyes with chronic central serous chorioretinopathy (cCSC) eyes with macular neovascularization (MNV) using ultra-widefield swept-source optical coherence tomography angiography (UWF SS-OCTA).
methodsThis retrospective comparative study included 46 cCSC with MNV eyes (With MNV group), 52 cCSC without MNV eyes (Without MNV group), and 40 age-matched healthy controls. UWF SS-OCTA imaging with a 20 mm×24 mm protocol was used to quantify CVI across 9 subfields (superotemporal, superior, superonasal, temporal, central, nasal, inferotemporal, inferior, and inferonasal). The CVI was compared among the groups.
resultsWith MNV group demonstrated significantly older mean age than Without MNV group (56.2±6.1
conclusionCVI decreases, and choroidal structural changes extend beyond the subfoveal area in cCSC with MNV eyes, providing with an imaging evidence for the important role of choroidal ischemia in the pathogenesis of MNV in cCSC.
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