ArticleInternational journal of ophthalmology2025
Simultaneous versus sequential corneal cross-linking and intracorneal ring segments implantation for keratoconus: two-year study.
Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Timing of corneal cross-linking in eyes undergoing intracorneal ring segments for keratoconus: same-day versus staged CXL: a systematic review and meta-analysis.International ophthalmology · 2026Pooled it
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare simultaneous corneal collagen cross-linking (CXL) with intracorneal ring segment (ICRS) implantation versus successive ICRS followed by CXL and detect the impact of the timing of CXL after ICRS implantation in the successive method.
methodsThis is a retrospective study of the records of three groups of patients. Group 1 of 28 patients were operated on with simultaneous ICRS implantation and CXL, group 2 of 32 patients had ICRS implantation followed by CXL after 1mo, and group 3 of 38 patients had ICRS implantation followed by CXL after 3mo. The three groups had follow-up visits after 6, 12, and 24mo.
resultsThe preoperative data, age, and gender differences among 3 groups revealed no significant differences. The postoperative spherical equivalent and best-corrected visual acuity were improved significantly in all groups compared to the baseline, which were more evident in groups 1 and 2. The differences between preoperative and postoperative mean values of mean of K readings (Km) and maximum K reading (Kmax) at 6mo were 4.66 and 4.1 D in group 1, 4.43 and 4.64 D in group 2, but 3.2 and 3.4 D in group 3, respectively. The spherical aberrations and the vertical coma showed significant postoperative changes in all groups, and trefoil showed nonsignificant changes.
conclusionSimultaneous and sequential ICRS implantation and CXL at 1mo has similar Km and Kmax better postoperative changes than when both surgeries were done at three-month intervals.
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