ArticleAmerican journal of translational research2025
H3K9me3 and H3K27me3 are epigenetic barriers to somatic cell nuclear transfer in rabbits.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Dynamic Balance of Histone H3 Methylation: Regulatory Mechanisms and Therapeutic Prospects in RA Immune Dysregulation and Bone Metabolism Imbalance.Journal of immunology research · 2026Review
- Neuron-specific WDR5 epigenetically upregulates ARID5B to impair GABAergic synaptic transmission and promotes epileptogenesis.Theranostics · 2026Article
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Authors and funding
10 authors.
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Abstract
Somatic cell nuclear transfer (NT) is associated with aberrant changes in epigenetic reprogramming that disrupt embryo development. Here, we characterized the epigenetic patterns of histone 3 lysine 9 trimethylation (H3K9me3) and histone 3 lysine 27 trimethylation (H3K27me3), the repressive histone signature in heterochromatin, in NT rabbit embryos. H3K9me3 modification was higher in all stages of NT vs. fertilized preimplantation embryos, consistent with decreased transcription of the H3K9me3 demethylase
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