ArticleAmerican journal of translational research2025
Combination of keloid core excision and triamcinolone acetonide local injection shows significant clinical efficacy in treating auricular keloid.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo investigate the clinical efficacy of keloid core excision combined with triamcinolone acetonide (TA) local injection for the treatment of auricular keloids.
methodsFrom May 2019 to November 2021, 86 patients with auricular keloid who met the inclusion criteria were enrolled. Based on treatment modality, they were divided into two groups: a research group (n=43) receiving keloid core excision combined with TA local injection and a control group (n=43) undergoing keloid core excision alone. The clinical efficacy, postoperative adverse reactions, Vancouver Scar Scale (VSS) score 12-Item Pruritus Severity Scale (12-PSS) score, sleep quality, serological indicators, Self-Rating Anxiety Scale (SAS) score, Self-Rating Depression Scale (SDS) score, Short-Form 36-Item Health Survey (SF-36) scores, recurrence rate, and treatment satisfaction were compared between the two groups.
resultsThe research group showed superior overall clinical efficacy, higher SF-36 scores, fewer total adverse reactions, and better sleep quality compared to the control group. Additionally, the research group had lower VSS, 12-PSS, SAS, and SDS scores, more significant reductions in serological indicators, and a reduced recurrence rate.
conclusionsKeloid core excision combined with TA local injection was more effective than keloid core excision alone in treating auricular keloids, with significantly better clinical efficacy.
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