ArticleFrontiers in cellular and infection microbiology2025
Microbial shifts in dental plaque of children with severe early childhood caries following comprehensive dental treatment under general anesthesia.
Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To elucidate the microbial diversities and compositions of dental plaque in children with severe early childhood caries (S-ECC) before and after comprehensive dental treatment under general anesthesia, contributing evidence for the reestablishment of oral microecological balance. Design: Twenty children aged 2.2-5.5 years diagnosed with S-ECC without systemic diseases were enrolled in this study. Dental plaque samples were collected before and after treatment, analyzed using high-throughput sequencing on the Illumina Miseq platform. Bioinformatics methods were employed to compare the dental plaque microbial diversity and compositions differences before and after comprehensive dental treatment under general anesthesia. Results: Significant enhancements in dental plaque microbial diversity were observed post-comprehensive treatment ( Conclusions: Following comprehensive dental treatment under general anesthesia, children with S-ECC exhibit significant changes in the microbial diversity and composition of dental plaque, indicating a shift towards a more balanced oral microecological state. This study highlights the importance of dental intervention in positively altering oral microbiota.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.