ArticleFrontiers in cardiovascular medicine2025
Evaluation of fetal cardiac morphology and function in hypertensive disorders of pregnancy using Fetal HQ technology combined with uterine artery ultrasound parameters.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Hypertensive disorders of pregnancy (HDP) significantly affect both maternal and fetal health, with uterine artery hemodynamic parameters playing a critical role in assessing fetal well-being, though they do not provide early insights into fetal cardiac function. Fetal Heart Quantification (Fetal HQ) technology offers a non-invasive, highly accurate method for evaluating fetal heart morphology and function, making it a valuable tool for assessing the impact of HDPs on fetal cardiac health. Methods: This study investigates fetal heart function and morphology in hypertensive disorders of pregnancy (HDPs) using fetal heart quantification (HQ) technology combined with uterine artery ultrasound parameters. A total of 70 normal fetuses and 59 fetuses with HDPs were included, with 30 cases showing normal and 29 cases showing abnormaluterine artery blood flow patterns. Uterine artery hemodynamic parameters (PI, RI, S/D) and fetal echocardiographic parameters (FRAC, FS, GLS, EF, 4CVCirc, GSI) were assessed. Results: Results showed that in the HDP group with abnormal uterine artery blood flow, PI, RI, and S/D were significantly higher than in both the control and HDP groups with normal blood flow ( Conclusion: These findings suggest that the fetal right ventricle is more sensitive to hemodynamic changes in HDP pregnancies, with right heart functional and morphological indicators potentially serving as predictive markers.
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