ArticleJournal of cancer research and oncobiology2024
Therapeutic Potential of Ceramide in Cancer Treatment.
Article in Journal of cancer research and oncobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
Abstract
Ceramides are a family of wax-like lipids that fall under the broader category of sphingolipids. A ceramide is composed of a sphingosine side chain coupled to a fatty acid via an amide linkage. Distinct from complex sphingolipids, the head of ceramide is a simple alcohol rather than a phosphate, phosphocholine, sugar, or more. The fatty acid chains of ceramide can also vary in chain length and degree of saturation. The degree of saturation may determine the biological activity of the ceramide species. Ceramides are highly abundant within the cell membrane of eukaryotic cells and are appreciated for their structural roles in these cells. Moreover, ceramides are well-known for their biological activity including as regulators of apoptosis, senescence, the cell cycle, and differentiation. This review discusses pathways of ceramide, roles of ceramide in various diseases, targeting ceramide metabolism in the treatment of cancer, as well as ceramide-delivering nanotechnologies.
Indexed as
Identifiers
40384804PMC12083856What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.