Evidence map›Paper›PMID 40384801›Full record

ArticleInfection and drug resistance2025

Diagnosis of Mycoplasma Hominis Peritonitis in a CAPD Patient with Metagenomic Next-Generation Sequencing: A Case Report.

Chunfeng Deng, Lei Hong, Dongni Sun, Hui Miao, Fei Tang, Zhaohui Li, Xi Liu

Abstract readCase Reports
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chunfeng DengDepartment of Nephrology, Longgang Central Hospital of Shenzhen, Shenzhen, 518116, People's Republic of China.
Lei HongDepartment of Nephrology, Longgang Central Hospital of Shenzhen, Shenzhen, 518116, People's Republic of China.
Dongni SunDepartment of Nephrology, Longgang Central Hospital of Shenzhen, Shenzhen, 518116, People's Republic of China.
Hui MiaoDepartment of Nephrology, Longgang Central Hospital of Shenzhen, Shenzhen, 518116, People's Republic of China.
Fei TangDepartment of Nephrology, Longgang Central Hospital of Shenzhen, Shenzhen, 518116, People's Republic of China.
Zhaohui LiDepartment of Nephrology, Longgang Central Hospital of Shenzhen, Shenzhen, 518116, People's Republic of China.
Xi LiuDepartment of Nephrology, Longgang Central Hospital of Shenzhen, Shenzhen, 518116, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mycoplasma hominis (Mh) is a conditional pathogenic microorganism in humans, typically colonizing the genitourinary tract of adults and causing infections in this system. However, Mh is rarely reported as a causative agent of peritoneal dialysis (PD)-associated peritonitis. Case Presentation: A 46-year-old woman undergoing maintenance PD presented with abdominal pain and cloudy PD effluent. Her PD modality is continuous ambulatory peritoneal dialysis (CAPD). Cultures of the PD effluent and blood were negative, and empirical antibiotic therapy was ineffective, leading to a diagnosis of refractory peritonitis. Metagenomic next-generation sequencing (mNGS) detected Mh in the PD effluent. Treatment was adjusted to intraperitoneal (IP) clindamycin combined with intravenous drip(ivdrip) moxifloxacin, resulting in complete recovery. Conclusion: Patients with culture-negative PD-associated peritonitis or refractory peritonitis should be evaluated for potential Mh infection. mNGS enables rapid detection of pathogens that traditional methods may fail to identify. A combination of moxifloxacin and clindamycin is effective for treating PD-associated peritonitis caused by Mh.

Indexed as

metagenomic next-generation sequencingmycoplasma hominisperitoneal dialysis-associated peritonitis

Identifiers

PMID40384801
PMCPMC12083492

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