Evidence map›Paper›PMID 40384781›Full record

ReviewFrontiers in microbiology2025

The role of intestinal microbiota and its metabolites in the occurrence and intervention of obesity.

Yang Gao, Wenhui Liu, Xue Ma, Min Xue, Yingying Li, Shanshan Bi, Huan Leng

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yang Gao *College of Life Science, Baicheng Normal University, Baicheng, China.
Wenhui Liu *Xiamen Jinfen Agricultural Research Institute, Xiamen, China.
Xue Ma *College of Life Science, Baicheng Normal University, Baicheng, China.
Min XueCollege of Life Science, Baicheng Normal University, Baicheng, China.
Yingying LiCollege of Life Science, Baicheng Normal University, Baicheng, China.
Shanshan BiCollege of Life Science, Baicheng Normal University, Baicheng, China.
Huan LengTerra Research and Teaching Centre, Microbial Processes and Interactions (MiPI), Gembloux Agro-Bio Tech, University of Liège, Gembloux, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a growing global health challenge influenced by genetic and environmental factors. With economic development, obesity rates continue to rise globally. Recent research highlights the critical role of gut microbiota in obesity pathogenesis, particularly through microbial metabolites affecting metabolism and energy homeostasis. Recent studies indicate that gut microbiota significantly influences obesity development through metabolic interactions, including the regulation of glucose and lipid metabolism. Gut microbiota is involved in the metabolism of various nutrients such as glucose and lipids, and the change of gut microbiota leads to insulin resistance, adipose tissue accumulation and metabolic disorders, thus mediating the occurrence and development of metabolic diseases. For example, beneficial bacteria such as

Indexed as

gut microbial metabolitesgut microbiotametabolic diseasesmetabolic disordersobesity

Identifiers

PMID40384781
PMCPMC12081357

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.