ArticleQuantitative imaging in medicine and surgery2025
Depicting growth characteristics with computed tomography for KRAS-mutated lung adenocarcinoma.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Kirsten rat sarcoma viral oncogene homolog (KRAS) is a key oncogenic driver in lung adenocarcinoma (LUAD). The correlation between KRAS mutations and the computed tomographic (CT) texture features in LUAD patients is not well established. This study aimed to investigate the relationship between the CT texture features of LUAD and the KRAS mutation. Methods: This study included 808 LUAD patients who were diagnosed with the KRAS mutation and underwent surgical resection at the Huadong Hospital. Of the 808 patients, 720 had preoperative chest CT data, which were collected for retrospective analysis. Further, all the CT images of lesions were classified into different categories based on the CT texture features. Moreover, the association between KRAS status and the clinical features and CT texture features was evaluated. Results: The results revealed that KRAS mutations were more common in the male patients than the female patients [8.5% (29/341) Conclusions: This study revealed that KRAS mutations were more common in male and older LUAD patients. Further, in most LUAD patients with KRAS mutations, pGGOs changed into pSOs at the size of >1 cm at least.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.