ArticleQuantitative imaging in medicine and surgery2025
Free-breathing pediatric cardiac dark-blood imaging with reverse double inversion-recovery and single-shot deep learning reconstruction.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- The role of artificial intelligence in pediatric cardiovascular imaging: clinical applications and future directions in computed tomography and magnetic resonance imaging.Pediatric radiology · 2026Review
- Clinical applications of co-registered myocardial T2 mapping and dual bright- and black-blood late gadolinium enhancement magnetic resonance imaging.European heart journal. Imaging methods and practice · 2026Article
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8 authors.
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Abstract
Background: Dark-blood T2-weighted fast spin-echo (DB-FSE) is sensitive to motion, leading to signal dropout artifacts and ghosting artifacts in free-breathing pediatric cardiac imaging, which severely impairs its diagnostic quality. Here, we aimed to fulfill high-resolution motion-robust edema assessment during free-breathing by combining reverse double inversion recovery (RDIR) and single-shot DB-FSE based on artificial intelligence (AI)-assisted compressed sensing (ACS) reconstruction. Methods: This prospective study included 20 healthy children and 47 pediatric patients. Three imaging techniques were compared: routine multi-shot DB-FSE based on double inversion recovery (MS-DIR), multi-shot DB-FSE based on RDIR (MS-RDIR), and single-shot DB-FSE based on RDIR (SS-RDIR) with ACS reconstruction. These methods were compared via quantitative metrics, including total acquisition time, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR), and qualitative metrics, including myocardial visibility, ghosting artifacts, and overall quality. Results: In healthy children, the total acquisition time (seconds) of SS-RDIR (64.8±21.8) was significantly less than those of MS-DIR (222.5±69.3, P<0.001) and MS-RDIR (234.0±64.1, P<0.001). The SNR and CNR were comparable (P=0.094 for SNR and P=0.054 for CNR). Ghosting artifacts were significantly reduced in SS-RDIR (4.70±0.18) compared to MS-DIR (3.95±0.28, P<0.001) and MS-RDIR (3.97±0.31, P<0.001), whereas overall quality was improved in SS-RDIR (4.42±0.19) compared to MS-DIR (3.87±0.27, P=0.004) and MS-RDIR (3.95±0.34, P=0.010). In patients, SS-RDIR significantly reduced the total acquisition time compared to MS-DIR (62.1±24.0 Conclusions: SS-RDIR with ACS reconstruction offers substantially shorter scan time and superior image quality than traditional multi-shot techniques. This approach enhances clinical workflow and patient comfort, facilitating a broader application of DB-FSE in pediatric cardiac imaging.
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