ArticleQuantitative imaging in medicine and surgery2025
Contrast-enhanced ultrasound combined with shear wave elastography in the diagnosis of C-TIRADS category 4 thyroid nodules.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic value of contrast-enhanced ultrasound combined with other imaging techniques in differentiating benign and malignant thyroid nodules: a network meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Article
- The combination of virtual touch tissue imaging quantification (VTIQ) and American College of Radiology's Thyroid Imaging Reporting and Data System (ACR TI-RADS) improves the diagnostic efficiency for thyroid nodules with Hashimoto's thyroiditis: a retrospective study.Quantitative imaging in medicine and surgery · 2026Article
- Shear wave elastography combined with fine-needle aspiration biopsy in the diagnosis of China Thyroid Imaging Reporting and Data System category 4 thyroid nodules.Gland surgery · 2026Article
- Artificial intelligence and elastography in diagnostic work-up of thyroid nodules: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2026Article
- Application of fine-needle aspiration biopsy combined with multi-gene testing in the differential diagnosis of benign and malignant C-TIRADS 4 thyroid nodules.Frontiers in medicine · 2026Article
- Contrast-enhanced ultrasound thyroid imaging reporting and data system outperforms K-TIRADS in diagnostic accuracy and reduces unnecessary fine-needle aspirations for thyroid nodules.Frontiers in endocrinology · 2026Article
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6 authors.
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Abstract
Background: Contrast-enhanced ultrasound (CEUS) and shear wave elastography (SWE) have been widely used in the diagnosis of thyroid nodules. The main purpose of this study was to investigate the diagnostic value of CEUS combined with SWE for Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) category 4 thyroid nodules. Methods: CEUS and SWE were performed on 219 patients with 219 C-TIRADS category 4 thyroid nodules. Receiver operator characteristic (ROC) curves were drawn based on the surgical and pathological results. The diagnostic efficacy of CEUS, SWE, and CEUS and SWE combined were analyzed and compared. Results: The areas under the curve (AUCs) of the ROC curves for CEUS and SWE were 0.899 [95% confidence interval (CI): 0.847-0.951] and 0.838 (95% CI: 0.775-0.901), respectively. The diagnostic sensitivity, specificity, accuracy, negative predictive value (NPV), positive predictive value (PPV), positive likelihood ratio (LR Conclusions: For C-TIRADS category 4 thyroid nodules, CEUS and SWE had high diagnostic efficacy, and the combination of CEUS and SWE further increased the diagnostic sensitivity, NPV, and accuracy, and thus could be used to help guide the treatment and management of patients.
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