ArticleQuantitative imaging in medicine and surgery2025
The rationale for proposing a magnetic resonance slow diffusion metric and its proof-of-concept testing showing spleen parenchyma and hepatocellular carcinoma have faster diffusion than liver parenchyma.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Relationships among slow diffusion coefficient and diffusion-derived 'vessel density' signal features, Gadoxetate delayed enhancement, tumor size, tumor grading, and patient survival: an exploratory study of mass-forming intrahepatic cholangiocarcinoma.Journal of gastrointestinal oncology · 2026Article
- The value of non-enhanced magnetic resonance imaging based on T2-weighted imaging and apparent diffusion coefficient in the study of three-tiered HER2 status in patients with breast cancer.Quantitative imaging in medicine and surgery · 2026Article
- The role of number-of-excitations (NEX) for the usability of free-breathing acquired diffusion-derived 'vessel density' (DDVD) and slow diffusion coefficient (SDC) maps in separating liver cysts, hemangiomas, and solid masses with a focus on small lesions.Journal of gastrointestinal oncology · 2026Article
- Classification of hepatocellular carcinoma Ki-67 expression status by a simple combination of magnetic resonance slow diffusion coefficient (SDC) and apparent diffusion coefficient (ADC): initial promising results.Quantitative imaging in medicine and surgery · 2026Article
- The impacts of time of echo and time of repetition on slow diffusion coefficient (SDC) measure and the potential age- and gender-related variations in liver and spleen SDC values: studies of healthy volunteers.Quantitative imaging in medicine and surgery · 2026Article
- Separation of liver focal nodular hyperplasia (FNH) and liver malignant tumors by a combination of T2-weighted imaging signal and three diffusion magnetic resonance metrics of diffusion-derived vessel density, slow diffusion coefficient, and apparent diffusion coefficient.Journal of gastrointestinal oncology · 2026Article
- Reliable diagnosis of liver focal nodular hyperplasia by a combination of T2 weighted signal and three diffusion magnetic resonance metrics of diffusion-derived 'vessel density', slow diffusion coefficient, and apparent diffusion coefficient: a validation study of two centers' data.Quantitative imaging in medicine and surgery · 2026Article
- Improvement of magnetic resonance imaging diffusion metric 'slow diffusion coefficient (SDC)' over apparent diffusion coefficient (ADC) for isocitrate dehydrogenase (IDH) genotyping in diffuse gliomas.Quantitative imaging in medicine and surgery · 2026Article
- Added value of slow diffusion coefficient (SDC) for the separation of benign and malignant parotid gland tumors by diffusion weighted imaging: preliminary results.BMC medical imaging · 2025Article
- An explanation for why tissues with T2 of around 70 milliseconds always measure low MRI apparent diffusion coefficient (ADC).Quantitative imaging in medicine and surgery · 2025Article
- Quantitative metrics of mean apparent propagator magnetic resonance imaging in the diagnosis of axillary lymph node metastasis in breast cancer.Quantitative imaging in medicine and surgery · 2025Article
- A combination of MRI diffusion-derived vessel density (DDVD) and slow diffusion coefficient (SDC) can reliably diagnose liver hemangioma: a testing of three centers' data.Journal of gastrointestinal oncology · 2025Article
- A novel MRI diffusion metric 'slow diffusion coefficient' (SDC) for diagnosing isocitrate dehydrogenase (IDH) genotype in diffuse gliomas: initial promising results.BMC medical imaging · 2025Article
- Prospective comparison of synthetic high b-value field of view optimized and constrained undistorted multiplexed sensitivity encoding (FOCUS-MUSE) and FOCUS diffusion-weighted imaging in evaluating cervical cancer.Quantitative imaging in medicine and surgery · 2025Article
- MRI slow diffusion coefficient (SDC) shows liver pyogenic abscess has faster diffusion than adjacent liver parenchyma.Quantitative imaging in medicine and surgery · 2025Article
- Lower diffusion-derived vessel density (DDVD) measure of liver focal nodular hyperplasia than those of hepatocellular carcinoma and liver metastasis allows potential differential diagnosis: quantitative and semi-quantitative analyses of two-center data.Journal of gastrointestinal oncology · 2025Article
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Abstract
Background: The liver and spleen have a similar amount of blood perfusion, and the spleen is waterier than the liver. The spleen tissue has a higher contrast-enhanced computed tomography (CT) extracellular volume fraction than the liver. The spleen has been reported to have a much lower apparent diffusion coefficient (ADC), intravoxel incoherent motion (IVIM)-perfusion fraction (PF), and IVIM-D Methods: This study utilized a random selection of authors' historical liver IVIM magnetic resonance imaging (MRI) data. For 1.5T data, SDC was calculated with Results: The median ratio of SDC Conclusions: The spleen has a faster diffusion than the liver, HCCs have a faster diffusion than the adjacent liver parenchyma, and hemangiomas have a faster diffusion than simple cysts. Although it is known that cysts have a substantially longer T2 than hemangiomas, SDC of hemangioma was higher than that of cysts, suggesting 'T2 effect' is minimized for SDC.
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