Evidence map›Paper›PMID 40384602›Full record

ArticleThe Laryngoscope2025

Long-Term Cochlear Implant Sensitivity in Patients With Far Advanced Otosclerosis.

Raphaële Quatre, Åsa Bonnard, Jeremy Wales, Martin Eklöf

Abstract read
In one paragraph

Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raphaële QuatreDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital, Grenoble Alpes, France.ORCID 0000-0002-3877-121X
Åsa BonnardDepartment of CLINTEC, Div of Otorhinolaryngology, Karolinska Institutet, Stockholm, Sweden.
Jeremy WalesDepartment of CLINTEC, Div of Otorhinolaryngology, Karolinska Institutet, Stockholm, Sweden.
Martin EklöfDepartment of CLINTEC, Div of Otorhinolaryngology, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCochlear implantation in otosclerosis patients presents unique surgical and programming challenges. The success and satisfaction of these patients heavily depend on precise speech processor fitting. Increased bone growth and tissue mass associated with otosclerosis can hinder electrical current flow, adding resistance to stimuli transmission to ganglion cells. This study aimed to evaluate mid- and long-term cochlear implant fitting in otosclerosis patients compared to a control group.

methodsThis was a monocentric retrospective case-control study conducted at a tertiary referral center comparing patients with far advanced otosclerosis and a control group of post-lingually deafened individuals from the same database. Data collected included: age, sex, etiology, hearing deprivation duration, implantation age and side, surgical details, postoperative complications (e.g., tinnitus, dizziness, or facial nerve stimulation), hearing tests, and cochlear implant fitting details.

resultsThe study analyzed 80 patients: 29 with otosclerosis and 51 controls. Higher impedances were seen in the otosclerosis group at 2 and 5 years, statistically significant for basal, middle, and overall electrodes at 2 years. Higher C- and T-levels for apical electrodes at 2 years were identified, and neural response telemetry thresholds were significantly higher for medial and apical electrodes in otosclerosis patients at 2 years. Despite these differences, auditory outcomes at 5 years were comparable between groups.

conclusionThese findings suggest significant tissue remodeling at the cochlear apex in otosclerosis patients, likely increasing resistance to electrical currents delivered by the implant. This highlights the importance of tailored programming and long-term monitoring for otosclerosis patients. LEVEL OF EVIDENCE: Level 3.

Indexed as

Cochlear ImplantationCochlear ImplantsOtosclerosisAdultAgedAuditory ThresholdCase-Control StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesTime Factorscochlear implantationcochlear implant fittingfar advanced otosclerosishearing outcomes

Identifiers

PMID40384602
PMCPMC12475534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.