Evidence map›Paper›PMID 40384287›Full record

ArticleJournal of veterinary internal medicine

Prevention of Subclinical Hypocalcemia in Holsteins Fed an Anionic Diet and Treated With Two Calcium Boluses at the Time of Calving.

Kemal Aksoy, Abdülkerim Deniz, Mert Metin, Mahmut Insel, Aytaç Pekmezci

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Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kemal AksoyDepertmant of Internal Medicine, Milas, Muğla Sitki Kocman University, Muğla, Turkey.ORCID https://orcid.org/0000-0003-0149-6688
Abdülkerim DenizFree Researcher for Clinical Biochemistry, Nisbetiye Mah. Bakır Sok. Beşiktaş, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-5242-5671
Mert MetinFaculty of Veterinary Medicine Milas, Depertmant of Biochemistry, Milas, Muğla Sitki Kocman University, Muğla, Turkey.ORCID https://orcid.org/0000-0002-1402-4594
Mahmut InselFree Researcher, Kahramandere Mah. Güzelbahçe, İzmir, Turkey.
Aytaç PekmezciFaculty of Science, Kötekli, Mugla Sitki Kocman University, Muğla, Turkey.ORCID https://orcid.org/0000-0003-4020-0069

Funding

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
6 · The paper itself

Abstract

backgroundThe incidence of subclinical hypocalcemia (iSCH) based on blood ionized calcium (iCa < 1.00 mmol/L) has not been investigated in Holsteins fed an anionic diet (AD) and non-AD prepartum and treated or not treated with calcium bolus (CB) around the time of calving. HYPOTHESIS: Anionic diets supported with CB at 12 h after calving should increase iCa and reduce iSCH better than AD + non-CB and non-AD + CB. ANIMALS: One hundred Holsteins were allocated to 4 groups: Group 1 (AD + CB), group 2 (AD + non-CB), group 3 (non-AD + CB) and group 4 (non-AD and non-CB).

methodsThe animals were randomly selected according to calving order. The iCa and iSCH were analyzed at calving before CB application on postpartum days (PPD) 1, 3, and 10. Urine pH was analyzed at calving and PPD1.

resultsUrine pH (6.43 ± 0.26), iCa (0.90 ± 0.16 mmol/L) and iSCH (50%) were significantly different in the combined AD groups compared to the non-AD groups at calving. Multiparous cows in combined AD groups had higher iCa and lower iSCH at calving. Group 1 had a higher iCa than groups 3 and 4. Group 2 had a higher iCa than Group 4 at PPD3. The iSCH of group 1 at PPD3 and 10 was lower than that of other groups. The iSCH decreased from 50% (PPD1) to 17% (PPD3) and 4% (PPD10) in group 1. Group 4 showed milk fever of 12%, 4%, and 4% at PPD1, 3, and 9, respectively.

conclusionGroup 1 was the most appropriate protocol to increase iCa, reduce iSCH, and prevent milk fever.

Indexed as

CalciumCattle DiseasesDietHypocalcemiaAnimal FeedAnimalsCattleFemaleParturitionPregnancyCalciumdairy cattleionized calciummetabolic acidificationmilk fever

Identifiers

PMID40384287
PMCPMC12086323

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.