Observational studyDiagnostic cytopathology2025
The Myriad Spectrum of Salivary Gland Lesions: Cytohistological Correlation on Fine Needle Aspiration Cytology, Core Needle Biopsy, and Resections in a 5-Year Single Institutional Experience of North India.
Observational study in Diagnostic cytopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The trial behind it
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Who cites it
2 citing papers in PubMed.
- Optimizing preoperative assessment of salivary gland lesions: updates and practical implications in the Milan System 2nd edition.Virchows Archiv : an international journal of pathology · 2026Review
- The Myriad Spectrum of Salivary Gland Lesions: Cytohistological Correlation on Fine Needle Aspiration Cytology, Core Needle Biopsy, and Resections in a 5-Year Single Institutional Experience of North India.Diagnostic cytopathology · 2025Observational
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFine needle aspiration cytology (FNAC) is a cost-effective method used for preoperative diagnosis of salivary gland lesions. Due to the wide range of tumor types, overlapping morphology, and limited cellularity, diagnosing salivary gland lesions on FNAC can be challenging. A pattern-based approach focusing on cellular and architectural features possible on core needle biopsy (CNB) can help refine differential diagnoses.
objectivesThis study aimed to assess the concordance between FNAC and histological diagnoses obtained from CNB, as well as examine the risk of malignancy (ROM), and evaluate the agreement between histopathological assessments and diagnoses of these lesions in both CNB and resection specimens. MATERIALS AND
methodsA retrospective observational study was conducted in the Department of Oncopathology at a tertiary cancer center of North India over a period of 5 years. Cases wherein diagnosis offered on two modalities-FNAC and CNB were-available, were included.
resultsA total of 105 cases were identified. Category VI was the predominant category (60.95%) and the ROM in categories II, III, and IV was higher compared to that mentioned in the Milan System for Reporting Salivary Gland Cytopathology. Correlation between FNAC and CNB was achieved in 78.1% of cases, and between CNB and the final diagnosis on resection specimen was attained in 100% of cases.
conclusionThe limitations of FNAC can be obviated by the utilization of CNB. Ancillary studies such as immunohistochemistry and/or cytogenetics wherever necessary can be smoothly applied on biopsy material, establishing the precise diagnosis and thereby providing definitive direction to further management.
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