Evidence map›Paper›PMID 40384184›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2025

Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management.

Sanoj Rejinold N, Goeun Choi, Geun-Woo Jin, Jin-Ho Choy

Abstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sanoj Rejinold NIntelligent Nanohybrid Materials Laboratory (INML), Department of Chemistry, School of Science and Technology, Dankook University, Cheonan, 31116, Republic of Korea.ORCID 0000-0002-7045-0563
Goeun ChoiIntelligent Nanohybrid Materials Laboratory (INML), Department of Chemistry, School of Science and Technology, Dankook University, Cheonan, 31116, Republic of Korea.ORCID 0000-0002-5424-8322
Geun-Woo JinR&D Center, Hyundai Bioscience Co. LTD., Seoul, 07990, Republic of Korea.
Jin-Ho ChoyIntelligent Nanohybrid Materials Laboratory (INML), Department of Chemistry, School of Science and Technology, Dankook University, Cheonan, 31116, Republic of Korea.ORCID 0000-0002-4149-7100

Funding

National Academy of Sciences, Republic of Korea
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected over 770 million people worldwide. The long-term effects of COVID-19 and their management have become important issues. Accumulating evidence indicates that post-COVID-19 syndrome, also known as long COVID, is not limited to respiratory symptoms but affects a wide range of systems, including neurological, cardiovascular, gastrointestinal, musculoskeletal, and reproductive systems etc. The social and economic losses associated with these effects are estimated to reach 3·7 trillion dollars in the United States alone. However, no treatment for long COVID has been developed. Herein, the literature on long COVID is comprehensively reviewed to examine the underlying causes. Additionally, evidence supporting the efficacy of nanoengineered niclosamide is presented, given its ability to counteract the underlying causes. Niclosamide is already Food and Drug Administration (FDA)-approved, and the nanoengineered one is a viable candidate for clinical trials for long COVID.

Indexed as

NanotechnologyNiclosamideCOVID-19COVID-19 Drug TreatmentHumansPandemicsPost-Acute COVID-19 SyndromeSARS-CoV-2Niclosamidebroad‐spectrum antiviral therapyCOVID‐19global impactlong COVIDnanoengineered niclosamidepost‐COVID‐19 syndrome

Identifiers

PMID40384184
PMCPMC12243710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.