Evidence map›Paper›PMID 40384070›Full record

ArticleHealthcare informatics research2025

Generative Pre-trained Transformer: Trends, Applications, Strengths and Challenges in Dentistry: A Systematic Review.

Sibyl Siluvai, Vivek Narayanan, Vinoo Subramaniam Ramachandran, Victor Rakesh Lazar

Abstract read
In one paragraph

Article in Healthcare informatics research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sibyl SiluvaiDepartment of Public Health Dentistry, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, Tamilnadu, India.
Vivek NarayananDepartment of Oral and Maxillofacial Surgery, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, Tamilnadu, India.
Vinoo Subramaniam RamachandranDepartment of Conservative Dentistry and Endodontics, R.V.S Dental College and Hospital, Tamilnadu, India.
Victor Rakesh LazarDepartment of Radio Diagnosis, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Tamilnadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe integration of large language models (LLMs), particularly those based on the generative pre-trained transformer (GPT) architecture, has begun to revolutionize various fields, including dentistry. Despite these promising applications, the use of GPT in dentistry presents several challenges. Ongoing research and the development of robust ethical frameworks are essential to mitigate these issues and enhance the responsible deployment of GPT technologies in clinical settings. Hence, this systematic review aims to explore the trends, applications, strengths, and challenges associated with the use of GPT in dentistry.

methodsArticles were selected if they contained detailed information on the application of GPT in dentistry. The search strategy used in systematic reviews follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Our search of databases and other sources yielded a total of 704 studies. After removing duplicates and conducting a full-text screening, 16 articles were included in the review. The methodological quality of the research was evaluated using the Critical Appraisal Skills Programme (CASP) checklist.

resultsOut of a total of 91 articles published on GPT in dentistry, 20 were editorials and 11 were narrative reviews; these were excluded, leaving 60 original research articles for further analysis. The articles were assessed based on the type of results they provided. Ultimately, 16 articles that reported positive findings with robust methodology were included in this review.

conclusionsThe results highlight mixed responses; therefore, further research on integration into clinical workflows must be conducted with extensive methodological rigor.

Indexed as

Artificial IntelligenceDentistryGenerative Artificial IntelligenceLarge Language ModelsNatural Language Processing

Identifiers

PMID40384070
PMCPMC12086441

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.