ArticleJournal of biophotonics2025
Comparative Analysis of Pulsed and Continuous Wave Modes in High-Intensity Laser Light Therapy: Implications for Deep Tissue Treatment.
Article in Journal of biophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Role of laser therapy in enhancing chemotherapy efficiency in breast cancer: low level laser therapy, photochemotherapy, and photodynamic therapy as promising treatments.Lasers in medical science · 2026Review
- Photobiomodulation and Low-Level Laser Therapy as Complementary Strategies in Diabetes Treatment.International journal of molecular sciences · 2026Review
- Comparative Analysis of Pulsed and Continuous Wave Modes in High-Intensity Laser Light Therapy: Implications for Deep Tissue Treatment.Journal of biophotonics · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
High-intensity laser at a wavelength of 1064 nm has gained significant attention in the field of therapeutic applications due to its potential to penetrate deeper. Continuous wave laser therapy, although effective, poses a challenge of elevated skin temperature. This study endeavors to explore the transition from continuous to pulsed laser, aiming to enhance light fluence in deep tissue while mitigating skin temperature rise. Investigating continuous versus pulsed wave in transdermal deep tissue light therapy, this research utilizes a high-intensity laser at 1064 nm to optimize fluence in deep muscle tissue of the human knee, minimizing absorption-driven skin temperature rise. Simulated parameters, including peak power (60 W), pulse width (2 ms), duty cycle (10%), frequency (50 Hz), as well as beam size of 20 mm, indicate that pulsed wave irradiation after 300 s achieved the lowest skin surface temperature (42.5°C) and the highest fluence (approximately 4.2 J/cm
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Registered trials
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