Evidence map›Paper›PMID 40383912›Full record

ArticleGut microbes2025

CD44 is a macrophage receptor for TcdB from

Zhuo Chen, Wenzi Zhang, Danni Wang, Ruiqin Luo, Yuexin Yao, Xiaoyang Tao, Lu Li, Qin Pan, Xiaoming Sun

Erratum issuedAbstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. A multifunctional probiotic co-delivery platform for the treatment of Clostridium difficile infection.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Zhuo ChenSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.
Wenzi ZhangSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.
Danni WangSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.
Ruiqin LuoSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.
Yuexin YaoSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.
Xiaoyang TaoBiomedical Research Institute, Hubei University of Medicine, Shiyan, China.
Lu LiSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.
Qin PanHubei Province Key Laboratory of Allergy and Immunology, TaiKang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan, China.ORCID 0000-0002-4210-2852
Xiaoming SunSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.ORCID 0000-0002-9546-6764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxin B (TcdB) is a critical virulence factor in

Indexed as

Bacterial ProteinsBacterial ToxinsClostridioides difficileHyaluronan ReceptorsInflammationMacrophagesAnimalsHumansMiceMice, Inbred C57BLMice, KnockoutNF-kappa BRAW 264.7 CellsBacterial ProteinsBacterial ToxinsCd44 protein, mouseHyaluronan ReceptorsNF-kappa BtoxB protein, Clostridium difficileCD44inflammationreceptorsuccinylationTcdB

Identifiers

PMID40383912
PMCPMC12091907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.