Evidence map›Paper›PMID 40383857›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Impact of baseline

Amir Karimzadeh, Kimberley Hansen, Stefan Hein, Bernhard Haller, Matthias M Heck, Robert Tauber, Calogero D Alessandria, Matthias Eiber, Isabel Rauscher

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amir KarimzadehDepartment of Nuclear Medicine, School of Medicine and Health, TUM University Hospital, Munich, Germany. amir.karimzadeh@uke.de.
Kimberley HansenDepartment of Nuclear Medicine, School of Medicine and Health, TUM University Hospital, Munich, Germany.
Stefan HeinDepartment of Nuclear Medicine, School of Medicine and Health, TUM University Hospital, Munich, Germany.
Bernhard HallerSchool of Medicine and Health, Institute of AI and Informatics in Medicine, Technical University of Munich, TUM University Hospital, Munich, Germany.
Matthias M HeckDepartment of Urology, School of Medicine and Health, TUM University Hospital, Munich, Germany.
Robert TauberDepartment of Urology, School of Medicine and Health, TUM University Hospital, Munich, Germany.
Calogero D AlessandriaDepartment of Nuclear Medicine, School of Medicine and Health, TUM University Hospital, Munich, Germany.
Matthias EiberDepartment of Nuclear Medicine, School of Medicine and Health, TUM University Hospital, Munich, Germany.
Isabel RauscherDepartment of Nuclear Medicine, School of Medicine and Health, TUM University Hospital, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis retrospective analysis evaluated the prognostic value of baseline

methodsData from 182 mCRPC patients with baseline

resultsBaseline bone tumor volume prognosticated leukocytopenia (HR 1.03 per 100 ml, p = 0.036), while the number of bone lesions was prognostic for anemia (HR 1.04 per 10 lesions, p < 0.001) and severe anemia (HR per 10 lesions 1.05, p = 0.009). Higher baseline hemoglobin correlated with reduced leukocytopenia (HR 0.74, p = 0.002), thrombocytopenia (HR 0.80, p = 0.033), and severe anemia (HR 0.52, p < 0.001). Baseline kidney dysfunction was linked to anemia (HR 2.46, p = 0.002) and severe anemia (HR 3.81, p = 0.023). Prior [

conclusionBaseline

Indexed as

Bone NeoplasmsHematologic DiseasesProstatic Neoplasms, Castration-ResistantAgedAged, 80 and overGlutamate Carboxypeptidase IIHumansLutetiumMaleMiddle AgedPrognosisProstate-Specific AntigenRadioisotopesRadiopharmaceuticalsRetrospective StudiesTumor BurdenGlutamate Carboxypeptidase IILutetiumLutetium-177PluvictoProstate-Specific AntigenRadioisotopesRadiopharmaceuticals[177Lu]Lu-PSMA-I&T; mCRPCBone tumor metricsHematologic toxicityPSMA radioligand therapy

Identifiers

PMID40383857
PMCPMC12491086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.