Evidence map›Paper›PMID 40383840›Full record

SynthesisUpdates in surgery2025

Impact of laparoscopic and open surgery on stoma formation and postoperative outcomes in elderly patients with obstructive colorectal cancer following self-expandable metallic stent placement: a systematic review and meta-analysis.

Konstantinos Kossenas, Riad Azzam Kouzeiha, Olga Moutzouri, Filippos Georgopoulos

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Konstantinos KossenasDepartment of Basic and Clinical Sciences, University of Nicosia Medical School, 21 Ilia Papakyriakou, 2414 Engomi, P.O. Box 24005, 1700, Nicosia, Cyprus. kossenaswork@gmail.com.
Riad Azzam KouzeihaDepartment of Medicine, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
Olga MoutzouriDepartment of Basic and Clinical Sciences, University of Nicosia Medical School, 21 Ilia Papakyriakou, 2414 Engomi, P.O. Box 24005, 1700, Nicosia, Cyprus.
Filippos GeorgopoulosDepartment of Basic and Clinical Sciences, University of Nicosia Medical School, 21 Ilia Papakyriakou, 2414 Engomi, P.O. Box 24005, 1700, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a leading cause of cancer-related mortality, particularly in elderly patients. Obstructive CRC, often treated with self-expandable metallic stents (SEMS) as a bridge to surgery, requires careful consideration of the surgical approach. This systematic review and meta-analysis compares laparoscopic surgery (LS) and open surgery (OpS) for managing obstructive CRC in patients aged 65 and older following SEMS placement. This age group is often underexamined in clinical studies, and the existing research frequently includes a heterogeneous mix of age groups, limiting its applicability to elderly populations. A comprehensive literature search was conducted through PubMed, Scopus, and Cochrane Library up to November 2024. Studies comparing LS and OpS outcomes in patients aged 65 and older who had SEMS placement were included. Outcomes, such as anastomotic leakage, ileus, mortality, postoperative complications, anastomosis rates, stoma construction, and wound infections were analyzed. The data from observational studies were synthesized using random-effects models. The meta-analysis of seven studies involving 326 patients (166 in laparoscopic and 160 in OpS) showed no significant differences between the two approaches in most postoperative outcomes. Specifically, for anastomotic leakage (OR = 0.65, 95% CI 0.18-2.28, P = 0.50, I

Indexed as

Colorectal NeoplasmsIntestinal ObstructionLaparoscopySelf Expandable Metallic StentsSurgical StomasAgedAged, 80 and overHumansMalePostoperative ComplicationsTreatment OutcomeColectomyElderly patientsLaparoscopicMinimally invasive surgeryObstructive colorectal cancerOpen surgerySelf-expandable metallic stent

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What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.