Evidence map›Paper›PMID 40383839›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Delayed diagnosis of myasthenia gravis caused by concurrent anxiety symptoms.

Valentina Gasparini, Daniele Mattavelli, Leonardo Pantoni

Abstract readCase Reports
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Valentina GaspariniNeuroscience Research Center, Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.
Daniele MattavelliNeurology Unit, Luigi Sacco University Hospital, Milan, Italy.
Leonardo PantoniNeuroscience Research Center, Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy. leonardo.pantoni@unimi.it.ORCID http://orcid.org/0000-0001-7357-8530

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyasthenia gravis (MG) is the most frequent autoimmune disorder of the neuromuscular junction. Patients with MG often have concomitant psychiatric complications, with high prevalence rate of depression and anxiety. These disturbances may sometimes delay the diagnosis of MG. Moreover, the prescription of drugs used in anxiety disorder, such as benzodiazepines, interferes with the correct function of the neuromuscular junction, and may determine worsening of the symptoms. CASE PRESENTATION: In this paper, we report the case of a 54-year-old woman with bulbar onset of MG and without circadian fluctuations who, during the COVID pandemic and partly consequent to it, was initially diagnosed with anxiety disorder, and treated with psychiatric drugs that eventually worsened the picture and led her to the emergency room.

conclusionOur case is an example of how a concurrent anxiety disorder may mask and postpone the diagnosis of MG in patients without a clear modification of symptoms during the day. Misdiagnosing MG with anxiety disorder may have severe consequences.

Indexed as

AnxietyAnxiety DisordersCOVID-19Delayed DiagnosisMyasthenia GravisFemaleHumansMiddle AgedAnxietyBenzodiazepinesDepressionDiagnosisMyasthenia gravis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.