Evidence map›Paper›PMID 40383534›Full record

Trial reportHospital pediatrics2025

Barriers, Facilitators, and Time Costs of Implementing a Pediatric Clinical Pathway Intervention.

Sara M Aziz, Kathleen Bonsmith, Ralph Gonzales, Andrew Auerbach, Angela Douglas, Madison Anderson, Sara Thompson, Yeelen Edwards, Sunitha V Kaiser

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Hospital pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Urinary tract infections in children.Nature reviews. Urology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sara M AzizDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Kathleen BonsmithDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Ralph GonzalesDepartment of Internal Medicine, University of California, San Francisco, San Francisco, California.
Andrew AuerbachDepartment of Internal Medicine, University of California, San Francisco, San Francisco, California.
Angela DouglasDepartment of Pediatrics, Oregon Health and Science University Hillsboro Medical Center, Hillsboro, Oregon.
Madison AndersonDepartment of Pediatrics, Hoops Family Children's Hospital, Huntington, West Virginia.
Sara ThompsonSociety of Hospital Medicine, Philadelphia, Pennsylvania.
Yeelen EdwardsDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Sunitha V KaiserDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.

Funding

The SIP Study: Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized ChildrenR33HL157804 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KAISER, SUNITHA VEMULA · 2022 to 2025
$2.3M
NHLBI NIH HHS R33 HL157804
6 · The paper itself

Abstract

objectivesClinical pathways can improve care and outcomes for children with respiratory illnesses. The Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized Children (SIP) trial is a multicenter, randomized trial of a high-efficiency pathway intervention in general and community hospitals. Our objective was to describe implementation fidelity, strategy use, time costs, barriers, and facilitators.

methodsWe conducted a mixed-methods study. Hospitals received clinical pathways (intervention) and used 5 implementation strategies: quality improvement (QI) mentor meetings, education, iterative changes, audit and feedback, and clinical decision support via electronic order sets. Data were collected through monthly surveys (11 months) of site leaders and recordings of mentor meetings. Quantitative data were analyzed using descriptive statistics, and qualitative data were analyzed using thematic content analysis.

resultsEighteen site leaders (from 18 hospitals) and 8 QI mentors participated. Monthly survey completion rates were 72% to 100%. Pathway implementation fidelity was high (94%). Implementation strategies with the highest use were QI mentor meetings, iterative changes, and electronic order sets. Audit and feedback had the lowest use, driven by information technology challenges and delays in data collection. Implementation time costs were approximately 14 hours per month, and data collection had the highest time cost. Implementation barriers included time limitations and stakeholder resistance to change. Facilitators included SIP study resources, engagement of multidisciplinary staff, and alignment with institutional goals.

conclusionsOur multicenter study provides detailed guidance on implementation fidelity, strategy use, time costs, barriers, and facilitators for general and community hospitals implementing high-efficiency pediatric pathway interventions.

Indexed as

Critical PathwaysQuality ImprovementAsthmaBronchiolitisChildHumansPneumonia

Identifiers

PMID40383534
PMCPMC12180955

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.