Evidence map›Paper›PMID 40383506›Full record

ArticleAmerican heart journal2025

Enhancing cardiac rehabilitation adherence through home-based rehabilitation and behavioral nudges: The ERA nudge study design and rationale.

Prerna Gupta, Dana R Fletcher, Josh Durfee, Monica Martinez, Amanda Hajoglou, Joy Waughtal, Sheana Bull, Pamela N Peterson

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in American heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03834155 (Enhancing Cardiac Rehabilitation Adherence Through Home-based Rehabilitation and Behavioral Nudges), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03834155 nacompletednot on this map

Enhancing Cardiac Rehabilitation Adherence Through Home-based Rehabilitation and Behavioral Nudges: ERA Nudge

TypeinterventionalSponsorDenver Health and Hospital AuthorityRan2019 to 2024Enrolled447ConditionsAcute Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Disease, Valvular DiseaseArmsHospital-based CR + Movn Application, Choice of Hospital or home-based CR + Movn Application, Hospital-based CR + Movn Application + Nudge, Choice of Hospital or home-based CR + Movn Application + Nudge
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Prerna GuptaDivision of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA. Electronic address: Prerna.gupta@ucsf.edu.
Dana R FletcherEvida Research Consulting, Inc., Golden, CO.
Josh DurfeeCenter for Health Systems Research, Denver Health and Hospital Authority, Denver, CO.
Monica MartinezCenter for Health Systems Research, Denver Health and Hospital Authority, Denver, CO.
Amanda HajoglouCenter for Health Systems Research, Denver Health and Hospital Authority, Denver, CO.
Joy WaughtalAdult & Child Center for Outcomes Research & Delivery Science (ACCORDS), University of Colorado School of Medicine, Aurora, CO.
Sheana BullmHealth Impact Lab, Department of Community and Behavioral Health, Colorado School of Public Health, Aurora, CO.
Pamela N PetersonCenter for Health Systems Research, Denver Health and Hospital Authority, Denver, CO; Anschutz Medical Center, Division of Cardiology, University of Colorado, Aurora, CO.

Funding

POSTGRADUATE TRAINING IN CARDIOVASCULAR RESEARCHT32HL007822 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BUTTRICK, PETER N., LEINWAND, LESLIE ANNE · 1996 to 2023
$6.2M
Enhancing cardiac and pulmonary rehabilitation adherence through home-based rehabilitation and behavioral nudges: ERA NudgeR33HL143324 · NHLBI · DENVER HEALTH AND HOSPITAL AUTHORITY · PI PETERSON, PAMELA N · 2019 to 2022
$2.9M
NHLBI NIH HHS R33 HL143324NHLBI NIH HHS T32 HL007822
6 · The paper itself

Abstract

backgroundCardiac rehabilitation (CR) continues to be under-utilized despite known benefits across the cardiovascular disease spectrum. Unfortunately, despite efforts to augment access, barriers persist in patient access to rehabilitation and ability to participate due to logistical challenges. A choice of home-based CR may present an appealing alternative that circumvents these known obstacles. Similarly, nudge reminders, or messages designed to elicit behavioral change, may improve adherence to CR. HYPOTHESIS: Providing a choice of home or hospital-based CR, and nudge reminders will improve adherence to CR in an urban safety net population.

designThe Enhancing Cardiac Rehabilitation Adherence through Home-Based Rehabilitation and Behavioral Nudges (ERA-Nudge) study utilizes a 2 × 2 factorial design to randomize eligible CR patients to usual care versus choice of home or hospital-based CR, and tailored nudge messages versus generic reminders to encourage healthy behavior. The study assesses the effectiveness of choice of CR location (ie, home versus hospital) and nudge messages in improving CR adherence. The study also uses an implementation framework to understand reach, adoption, implementation, and maintenance of this approach within the context of real-world care delivery in a pragmatic trial design. The enrollment was completed in May 2023, with a total of 447 patients. SUMMARY: The ERA-Nudge trial assesses the implementation, effectiveness, and safety of choice in CR location and nudge messaging to improve CR adherence. If successful, this approach can be easily disseminated and may inform future implementations for rehabilitation and other behavioral therapies.

trial registrationURL: https://clinicaltrials.gov; Unique identifier: NCT03834155.

Indexed as

Behavior TherapyCardiac RehabilitationHome Care ServicesPatient ComplianceAgedFemaleHealth BehaviorHumansMaleMiddle AgedPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicReminder Systems

Identifiers

PMID40383506
PMCPMC12781893

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.