Evidence map›Paper›PMID 40383048›Full record

ReviewCurrent opinion in neurobiology2025

Accessing the viscera: Technologies for interoception research.

Karen K L Pang, Rajib Mondal, Atharva Sahasrabudhe, Polina Anikeeva

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karen K L PangDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, United States; K. Lisa Yang Brain-Body Center, Massachusetts Institute of Technology, United States; McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States; Research Laboratory of Electronics, Massachusetts Institute of Technology, United States.
Rajib MondalK. Lisa Yang Brain-Body Center, Massachusetts Institute of Technology, United States; McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States; Research Laboratory of Electronics, Massachusetts Institute of Technology, United States; MIT-Harvard Graduate Program in Health Sciences and Technology, United States.
Atharva SahasrabudheK. Lisa Yang Brain-Body Center, Massachusetts Institute of Technology, United States; McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States; Research Laboratory of Electronics, Massachusetts Institute of Technology, United States.
Polina AnikeevaDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, United States; K. Lisa Yang Brain-Body Center, Massachusetts Institute of Technology, United States; McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States; Research Laboratory of Electronics, Massachusetts Institute of Technology, United States; Department of Materials Science and Engineering, Massachusetts Institute of Technology, United States. Electronic address: anikeeva@mit.edu.

Funding

Fusion of nanomagnetic and viral tools to interrogate brain-body circuitsDP1AT011991 · NCCIH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANIKEEVA, POLINA O · 2021 to 2025
$5.3M
NCCIH NIH HHS DP1 AT011991
6 · The paper itself

Abstract

Interoception, or the perception and regulation of body signals by the central nervous system, is critical for maintaining homeostasis and coordination of behaviors. Deciphering the mechanisms of interoception requires identifying pathways and decoding of diverse signals across the brain-body axis. These studies are enabled by tools to modulate and record physiological processes in the brain and visceral organs. While numerous advanced neurotechnologies are well-established in the brain, these techniques often offer limited utility for other organs, such as the gastrointestinal tract, heart, liver, or bladder. In this review, we highlight recent advances in technologies for recording and modulation of visceral organ physiology in small animals in vivo, with a focus on implantable bioelectronic organ interfaces that can be deployed in behaving animals. We discuss how such interfaces are made possible through innovations in materials and electronics and outline unmet technological challenges in interoception research.

Indexed as

BrainInteroceptionVisceraAnimalsHumans

Identifiers

PMID40383048
PMCPMC12353182

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.