Trial reportEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025
Postoperative swelling: influence of a negative pressure application in comparison to manual lymphatic drainage after total knee arthroplasty-a randomized controlled trial.
Trial report in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Efficacy of kinesiotaping during rehabilitation following total knee arthroplasty: a prospective randomised controlled trial.Journal of rehabilitation medicine · 2026Trial
- Effectiveness of topical vacuum assisted drainage in mandibular third molar surgeries: a randomized controlled clinical study.BMC oral health · 2025Trial
- Effectiveness of Manual Lymphatic Drainage After Total Knee Arthroplasty: A Systematic Review.Journal of clinical medicine · 2026Review
- Factors associated with early swelling after total knee arthroplasty and poor venous return : the impact of quadriceps strength, activity and preoperative anticoagulation.BMC musculoskeletal disorders · 2026Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePostoperative soft tissue swelling is a significant factor influencing outcome after total knee arthroplasty (TKA). This prospective study aims to investigate the influence of technical device assisted negative pressure therapy (NP) on early functional outcome after TKA. NP was therefore compared to manual lymphatic drainage (MLD).
methodsA total of 50 consecutive patients undergoing primary TKA were enrolled. 25 subjects per group were either treated by conventional MLD or NP. Primary outcome parameter was defined as circumference of the affected limb in cm postoperative up to seven days postoperatively. Secondary outcome parameters were: Duration of hospitalization, subjective perception of pain (measured via visual analogue scale, VAS), affected limb's ROM.
resultsNP showed an overall equivalent influence compared to MLD in reducing lower limb swelling, recovering of mobility and length of hospital stay after TKA. Moreover, the application of NP showed a significant decrease in overall pain perception compared to manual lymphatic drainage on day 2 and forth after surgery (p < .05).
conclusionsOur findings show that NP could be a useful device in clinical routine treating postoperative swelling after TKA. Its application is simple and effective for the patient. Particularly given the shortage of healthcare workers and physical therapists, there is a need for supportive measures that NP could fulfil.
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