Evidence map›Paper›PMID 40382693›Full record

ArticleArchives of Iranian medicine2025

Extraction and Characterization of Phenolic Acid Compounds of Zahidi and Khastawi Dates Seed Extract and Evaluation of their Antibacterial Activity.

Noor Ridha Kadhim, Mohammad Rabbani Khorasgani, Hussam Sami Awayid, Hamid Noorbakhsh

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Article in Archives of Iranian medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Noor Ridha KadhimDepartment of Cell and Molecular Biology & Microbiology, Faculty of Biological Sciences and Technology, University of Isfahan, Isfahan, Iran.ORCID 0009-0009-4785-076X
Mohammad Rabbani KhorasganiDepartment of Cell and Molecular Biology & Microbiology, Faculty of Biological Sciences and Technology, University of Isfahan, Isfahan, Iran.ORCID 0000-0002-4043-9216
Hussam Sami AwayidDepartment of Medical Laboratory, Institute of Technical Suwaira, Middle Technical University, Wasit, Iraq.
Hamid NoorbakhshDepartment of Cell and Molecular Biology & Microbiology, Faculty of Biological Sciences and Technology, University of Isfahan, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe date fruit is a remarkable source of nutraceuticals and bioactive compounds. Different types of phenolic compounds with high antioxidant capacity are found in date seed extract. Additionally, these compounds can be potential antibacterial agents to combat antibiotic resistance strains. Therefore, the main idea of the current study was to quantify five key phenolic acids in the ethanolic extract of Zahidi and Khastawi dates seed and to examine their antibacterial activity against methicillin-resistant

methodsThe concentration of gallic acid, ferulic acid, p-coumaric acid, sinapic acid and cinnamic acid in the seed extracts were determined by high performance liquid chromatography (HPLC). Then, antibacterial activity of date seed extracts was analyzed using well diffusion method. Furthermore, a scanning electron microscopy (SEM) analysis was performed to confirm the antibacterial effects of the seed extracts.

resultsPhenolic acids were found to be in the range of 10.59 to 33.65 µg mg

conclusionIt can be concluded that date seed extract can be considered as a potential source of antibacterial compounds for the drug discovery purposes.

Indexed as

Anti-Bacterial AgentsHydroxybenzoatesMethicillin-Resistant Staphylococcus aureusPlant ExtractsSeedsAntioxidantsChromatography, High Pressure LiquidCinnamatesCoumaric AcidsGallic AcidMicrobial Sensitivity TestsMicroscopy, Electron, ScanningPropionatesAnti-Bacterial AgentsAntioxidantsCinnamatescinnamic acidCoumaric Acidsferulic acidGallic AcidHydroxybenzoatesp-coumaric acidphenolic acidPlant ExtractsPropionatessinapinic acidDate seedDrug resistanceMethicillin-resistantPhenolic acidStaphylococcus aureus

Identifiers

PMID40382693
PMCPMC12085802

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