Evidence map›Paper›PMID 40382643›Full record

ReviewCardiovascular ultrasound2025

Echocardiographic imaging in patients with conduction system pacing.

Alexander Suchodolski, Ewa Jędrzejczyk-Patej, Wiktoria Kowalska, Michał Mazurek, Radosław Lenarczyk, Oskar Kowalski, Zbigniew Kalarus, Mariola Szulik

Abstract readReview
In one paragraph

Review in Cardiovascular ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander SuchodolskiDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland. alex.suchodolski@gmail.com.
Ewa Jędrzejczyk-PatejDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland.
Wiktoria KowalskaDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland.
Michał MazurekDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland.
Radosław LenarczykDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland.
Oskar KowalskiDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland.
Zbigniew KalarusDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland.
Mariola SzulikDepartment of Cardiology and Electrotherapy, Faculty of Medical Sciences, Silesian Center for Heart Diseases, Medical University of Silesia, ZabrzeKatowice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conduction system pacing (CSP), encompassing His-bundle pacing (HBP) and left bundle branch area pacing (LBBAP), revolutionizes cardiac pacing, allowing a more physiological left ventricular activation than conventional right ventricular (RV) pacing through electrode placed in RV apex, interventricular septum or right ventricular outflow tract. Echocardiography plays a pivotal role in patient assessment, primarily by measuring left ventricular ejection fraction (LVEF) to determine the pacing strategy in alignment with current guidelines. Clinical data, simulations and ongoing trials on CSP explore CSP viability across various LVEF conditions. CSP is supposed to defer pacing-induced cardiomyopathy (PiCM) associated with conventional right ventricular pacing (RVP). This paper aims to review the current literature regarding the use of echocardiography in CSP. Images from our experience in the echocardiographic lab were used throughout this document to show our proposals of imaging in CSP. Echocardiography may help to determine lead localization within the interventricular septum (IVS), customizing pacing to individual anatomy and electromechanical indices (like atro-ventricular delay) and evaluates often-overlooked valvular function, a potential PiCM contributor. Three-dimensional (3-D) echocardiography widens the knowledge of lead localization and valvular dysfunction, as well as dyssynchrony assessment. Dyssynchrony, crucial both to resynchronization per se and physiological stimulation is quantified via echocardiography, especially using speckle-tracking imaging. Baseline LVEF and follow-up observation of CSP effects: early in Global Longitudinal Strain (GLS), afterwards in LV volumes and LVEF may improve the future proper qualification of patients. Limited left atrial (LA) and right atrial (RA) strain assessments hold potential in the CSP qualification and response assessment context. Echocardiography complements other imaging modalities for comprehensive patient evaluation. Echocardiography is integral in the CSP clinical use, from patient selection (by showing subtle changes in myocardial function) to post-procedure follow-up (tricuspid regurgitation, LV and RV function, leads and synchrony assessment). GLS, assessed by speckle tracking imaging and profound 2D and 3D (lead placement, septum morphology and global heart function under CSP) analyses show promise in CSP outcome assessment, though standardization is needed.

Indexed as

Cardiac Pacing, ArtificialEchocardiographyEchocardiography, Three-DimensionalHeart Conduction SystemBundle of HisHeart VentriclesHumansStroke VolumeConduction system; Pacing; Echocardiography; Speckle tracking

Identifiers

PMID40382643
PMCPMC12085811

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.