Evidence map›Paper›PMID 40382632›Full record

ArticleSubstance abuse treatment, prevention, and policy2025

Response to a peer telehealth intervention for emergency department patients presenting with opioid use disorder or unintentional overdose: a stratified interrupted time series analysis.

Martha Tillson, Huiping Xu, Alan McGuire, Spencer Medcalf, Francesca L Beaudoin, Dennis P Watson

Abstract read
In one paragraph

Article in Substance abuse treatment, prevention, and policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Martha TillsonUniversity of Kentucky Center on Drug and Alcohol Research, 643 Maxwelton Court, Lexington, KY, 40506, USA. martha.tillson@uky.edu.
Huiping XuDepartment of Biostatistics and Health Data Science, School of Medicine, Indiana University, 410 W 10th St, Indianapolis, IN, 46202, USA.
Alan McGuireCenter for Health Information and Communication, Richard L. Roudebush VA Medical Center, 1481 W 10th St, Indianapolis, IN, 46202, USA.
Spencer MedcalfSpark Recovery, 9302 N Meridian St, Indianapolis, IN, 46260, USA.
Francesca L BeaudoinDepartment of Epidemiology, School of Public Health, Brown University, 121 S Main St, Providence, RI, 02903, USA.
Dennis P WatsonLighthouse Institute, Chestnut Health Systems, 221 W. Walton St, Chicago, IL, 60610, USA.

Funding

Project POINT: Effectiveness and Scalability of an Overdose Survivor InterventionR33DA045850 · NIDA · INDIANA UNIVERSITY INDIANAPOLIS · PI MCGUIRE, ALAN BENJAMIN, WATSON, DENNIS PAUL · 2018 to 2020
$1.9M
NIDA NIH HHS R33 DA045850NIDA NIH HHS R33DA045850
6 · The paper itself

Abstract

backgroundPeople in the United States who use opioids frequently use emergency department (ED) services. Some hospitals have begun placing peer recovery support specialists (PRSS) in EDs to support and advocate for patients and provide linkages to services, in an effort to reduce future presentations for opioid-related and other health problems related to substance use. However, evidence supporting the impact of PRSS services on reducing future ED presentations is limited, and even less is known about ED-based PRSS services delivered via telehealth.

methodsUsing records from a large Indiana-based hospital system, we conducted an interrupted time series (ITS) analysis of ED patients presenting for unintentional opioid overdose or other opioid-related issues. Over a five-year period, 2,542 unique ED visits were included across 12 hospitals. The primary outcome assessed was the impact of PRSS telehealth service implementation (comparing pre- and post-periods) on 30-day all-cause ED revisits. Analyses were also stratified by appropriate demographics.

resultsThere was no significant change in 30-day ED revisits between pre- and post-implementation of the PRSS telehealth program. Results of sex-stratified ITS indicated a significant change for females only, with decreasing log-odds of ED revisits post-program implementation (post-implementation slope OR = 0.911, p = 0.031; slope change OR = 0.874, p = 0.017).

conclusionsAlthough there was no detectable difference in overall ED revisits following program implementation, outcomes of stratified analyses suggested that the program may have been more impactful for females vs. males. Future research should examine the underlying mechanism of the observed sex differences to target behavioral change more effectively for all participants of telehealth PRSS services in ED settings.

Indexed as

Drug OverdoseEmergency Service, HospitalOpiate OverdoseOpioid-Related DisordersPeer GroupTelemedicineAdultFemaleHumansIndianaInterrupted Time Series AnalysisMaleMiddle AgedYoung AdultEmergency departmentInterrupted time seriesOpioid use disorderPeer recovery supportTelehealth

Identifiers

PMID40382632
PMCPMC12085845

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.