Evidence map›Paper›PMID 40382601›Full record

ArticleBMC public health2025

Long working hours at midlife and arterial stiffness at older age in a 24-year prospective cohort.

Carolina Braga Sisti, Mahée Gilbert-Ouimet, Mathilde Lavigne-Robichaud, Chantal Brisson, Alain Milot, Xavier Trudel

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carolina Braga SistiDepartment of Social and Preventive Medicine, Laval University, Quebec City, Canada.
Mahée Gilbert-OuimetCentre de recherche du CHU de Québec-Université Laval, Quebec City, Canada.
Mathilde Lavigne-RobichaudCentre de recherche du CHU de Québec-Université Laval, Quebec City, Canada.
Chantal BrissonDepartment of Social and Preventive Medicine, Laval University, Quebec City, Canada.
Alain MilotCentre de recherche du CHU de Québec-Université Laval, Quebec City, Canada.
Xavier TrudelDepartment of Social and Preventive Medicine, Laval University, Quebec City, Canada. xavier.trudel@crchudequebec.ulaval.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsThis study aims to examine whether long working hours, repeatedly assessed at midlife, is associated with higher arterial stiffness at older age in a 24-year prospective study of white-collar workers in Quebec City, Canada.

methodsThis study relied on a prospective cohort, initiated in 1991-1993 (T1) with two follow-ups after 8 years (T2, 1999-2001) and 24 years (T3, 2015-2018). Participants (N = 1,629, 51.3% women, mean age 37 ± 6.4 at T1) were randomly selected for arterial stiffness measurement at T3 using carotid-femoral pulse wave velocity (PWV). Long working hours (> 40 h/week) were assessed at T1 and T2. Mean differences in PWV were estimated using generalized linear models, accounting for sociodemographic factors, lifestyle-related risk factors, clinical factors and psychosocial stressors at work.

resultsAmong participants who remained actively employed over the study period (age range: 21-59 at T1), long working hours at T1 were associated with a + 0.54 m/s (95% CI: 0.05; 1.02) increase in PWV, while repeated exposure at T1 and T2 was associated with a + 1.50 m/s (95% CI: 0.78; 2.21) increase. No association was observed among participants who retired between T2 and T3.

conclusionThe present study suggests that exposure to long working hours during midlife is associated with higher arterial stiffness, among aging workers. Workplace preventive strategies reducing long working hours may be effective to mitigate long-term arterial stiffening.

Indexed as

Vascular StiffnessWork Schedule ToleranceAdultFemaleHumansMaleMiddle AgedProspective StudiesPulse Wave AnalysisQuebecRisk FactorsYoung AdultArterial stiffnessCardiovascular diseaseOccupational stressWork environment

Identifiers

PMID40382601
PMCPMC12084974

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.