Evidence map›Paper›PMID 40382578›Full record

ArticleBMC genomics2025

Hybrid sequencing reveals the genome of a Chrysochromulina parva virus and highlight its distinct replication strategy.

Delaney Nash, Christine N Palermo, Ichiro Inamoto, Trevor C Charles, Jozef I Nissimov, Steven M Short

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Delaney NashDepartment of Biology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada. d2nash@uwaterloo.ca.
Christine N PalermoDepartment of Biology, University of Toronto Mississauga, Mississauga, ON, L5L 1C6, Canada.
Ichiro InamotoDepartment of Biology, University of Toronto Mississauga, Mississauga, ON, L5L 1C6, Canada.
Trevor C CharlesDepartment of Biology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
Jozef I NissimovDepartment of Biology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada. jnissimov@uwaterloo.ca.
Steven M ShortDepartment of Biology, University of Toronto Mississauga, Mississauga, ON, L5L 1C6, Canada. steven.short@utoronto.ca.

Funding

Mitacs IT18981Natural Sciences and Engineering Research Council of Canada 2022-00329Natural Sciences and Engineering Research Council of Canada 2022-03066
6 · The paper itself

Abstract

Chrysochromulina parva (C. parva) is a eukaryotic freshwater haptophyte algae found in lakes and rivers worldwide. It is known to be infected by viruses, yet knowledge of the diversity and activity of these viruses is still very limited. Based on sequences of PCR-amplified DNA polymerase B (polB) gene fragments, Chrysochromulina parva virus BQ1 (CpV-BQ1) was the first known lytic agent of C. parva, and was considered a member of the virus family Phycodnaviridae, order Algavirales. However, the genome of a different C. parva-infecting virus (CpV-BQ2, or Tethysvirus ontarioense) from another virus family, the Mesomimiviridae, order Imitervirales, was the first sequenced. Here, we report the complete genome sequence of the putative phycodnavirus CpV-BQ1, accession PQ783904. The complete CpV-BQ1 genome sequence is 165,454 bp with a GC content of 32.32% and it encodes 193 open reading frames. Phylogenetic analyses of several virus hallmark genes including the polB, the late gene transcription factor (VLTF-3), and the putative A32-like virion packaging ATPase (Viral A32) all demonstrate that CpV-BQ1 is most closely related to other viruses in the phylum Megaviricetes within the order Algavirales, family Phycodnaviridae.

Indexed as

Genome, ViralPhycodnaviridaeVirus ReplicationPhylogenySequence Analysis, DNAAlgal virusesAlgaviralesdsDNA virusHaptophytePhycodnaviridaePrymnesiophyte

Identifiers

PMID40382578
PMCPMC12085832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.